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Centrally acting antihypertensive drugs. Present and future.

Author: van ZwietenP A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Moxonidine and rilmenidine, new centrally acting antihypertensives, are compared to classic drugs like clonidine. Moxonidine and rilmenidine have better side-effect profiles.
Paper Details　
Original Abstract of the Article :
The classic centrally acting antihypertensives such as clonidine, guanfacine and alpha-methyl-DOPA (via its active metabolite alpha-methyl-noradrenaline) induce peripheral sympathoinhibition and a fall in blood pressure as a result of alpha2-adrenoceptor stimulation in the brain stem. These drugs ha...See full text at original site
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引用元：
https://doi.org/10.3109/10641969909061015

データ提供：米国国立医学図書館（NLM）

Centrally Acting Antihypertensive Drugs: Past, Present, and Future

In the vast desert of hypertension research, finding effective and safe treatments is a perpetual challenge. This study delves into the world of centrally acting antihypertensive drugs, exploring their mechanisms of action, efficacy, and side effects. The authors provide a comprehensive overview of both classic and newer centrally acting antihypertensives, highlighting their strengths and limitations. The study emphasizes the importance of understanding the specific receptor targets and anatomical locations involved in the actions of these drugs, paving the way for the development of more targeted and effective treatments.

Navigating the Terrain of Hypertension Treatment

This study provides a roadmap for navigating the complex landscape of hypertension treatment, offering insights into the mechanisms of action and side effects of centrally acting antihypertensive drugs. The research highlights the need for careful consideration of individual patient factors, such as age, underlying conditions, and potential drug interactions, to optimize treatment outcomes.

A Journey Towards More Effective Hypertension Treatments

While centrally acting antihypertensive drugs have proven beneficial for some patients, further research is needed to develop more targeted and effective treatments with fewer side effects. This study serves as a stepping stone toward a future where hypertension can be effectively managed with minimal impact on patient quality of life.

Dr. Camel's Conclusion

This research journey through the desert of hypertension treatment reveals the complexities and challenges associated with finding effective medications. By understanding the nuances of centrally acting antihypertensive drugs, researchers can continue to refine treatment strategies and ultimately improve the lives of individuals battling this common condition.
Date :
  1. Date Completed 1999-12-01
  2. Date Revised 2019-11-03
Further Info :

Pubmed ID

10423108

DOI: Digital Object Identifier

10.3109/10641969909061015

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Languages

English

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