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Double-blind, randomised, multicentre endocrine trial comparing two letrozole doses, in postmenopausal breast cancer patients.
Author: BajettaE, BichisaoE, CelioL, Di LeoA, DowsettM, GuillevinL, MarchianòA, MartinettiA, PozziP, StaniS, ZilemboN
Original Abstract of the Article :
Letrozole is an orally competitive aromatase inhibitor. This double-blind, randomised, multicentre trial was carried out to evaluate the endocrine effects of two doses of letrozole, 0.5 mg versus 2.5 mg orally daily, in postmenopausal advanced breast cancer patients progressing after tamoxifen. The ...See full text at original site
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引用元:
https://doi.org/10.1016/s0959-8049(98)00392-x
データ提供:米国国立医学図書館(NLM)
Letrozole for Breast Cancer: A Journey Through the Desert of Hormone Therapy
We're delving into the arid landscape of hormone therapy for breast cancer, a challenging and often complex field of study. This double-blind, randomized, multicentre trial, like a meticulous expedition across a vast desert, investigated the endocrine effects of two different doses of letrozole, an aromatase inhibitor, in postmenopausal women with advanced breast cancer. The goal was to find the optimal dose, a hidden spring of effectiveness, to maximize treatment benefits while minimizing side effects.
Letrozole: A Potential Oasis in the Desert of Breast Cancer Treatment?
The researchers found that both doses of letrozole effectively suppressed estrogen levels, a crucial target for breast cancer treatment. Imagine a traveler finding a cool and refreshing oasis in the scorching desert. Letrozole, in this analogy, represents the oasis, offering relief from the hormonal imbalances that fuel breast cancer growth. However, the study also emphasized the need for further research to optimize the dosage and understand long-term effects.
Navigating the Desert of Breast Cancer Treatment with Precision
This research, like a map revealing a hidden path, provides valuable insights into the use of letrozole for breast cancer. The study highlights the potential benefits of letrozole as a hormonal therapy, but also underscores the importance of careful consideration of dosage and potential side effects. As we continue our exploration through the desert of breast cancer treatment, finding the right path for each patient is essential.
Dr.Camel's Conclusion
The desert of breast cancer treatment can be a difficult journey, but this research offers hope. Letrozole, like a hidden oasis in the desert, has shown promise as a hormonal therapy for breast cancer. However, as with all journeys through the desert, we must carefully navigate the terrain, understanding the potential benefits and risks to find the best path for each patient.
Date :
- Date Completed 1999-08-23
- Date Revised 2019-07-18
Further Info :
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