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Hormone replacement therapy affects body composition and leptin differently in obese and non-obese postmenopausal women.

Author: KristensenK, MosekildeL, PedersenS B, RichelsenB, VestergaardP

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study found that hormone replacement therapy (HRT) reduced fat accumulation over five years in postmenopausal women, compared to women who did not take HRT. The reduction in fat was greater in women who were not obese than in those who were obese. While HRT increased leptin levels, this increase was not independent of the decrease in fat mass. The study suggests that HRT may reduce fat accumulation, particularly in the trunk area, but this effect is not directly related to leptin.
Paper Details　
Original Abstract of the Article :
Leptin and oestrogen are both involved in the regulation of adipose tissue deposition and feeding behaviour. We investigated whether 5 years of hormone replacement therapy (HRT) affected serum leptin and body composition differently in 89 postmenopausal women treated with HRT compared with 178 contr...See full text at original site
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引用元：
https://doi.org/10.1677/joe.0.1630055

データ提供：米国国立医学図書館（NLM）

The Influence of Hormone Replacement Therapy in the Shifting Sands of Body Composition

Hormone replacement therapy (HRT), a common intervention for postmenopausal women, can be likened to a carefully crafted sandcastle, designed to protect against the erosion of time. This study investigates the impact of HRT on body composition and leptin levels, a hormone that plays a role in regulating appetite and metabolism. The study compares HRT-treated women to a control group, exploring the subtle effects of this therapy on the shifting sands of the body's composition.

A Balancing Act in the Desert of Hormones

The study reveals that HRT significantly reduces fat mass accumulation, particularly in the trunk region, compared to the control group. This suggests that HRT could have a positive impact on body composition, helping to maintain a healthy balance in the desert of hormonal changes.

Protecting Your Health in the Shifting Sands

This study highlights the importance of understanding the potential benefits and risks of HRT. It encourages open communication with healthcare providers to determine the best course of action for individual needs.

Dr.Camel's Conclusion

The desert of menopause can be a challenging landscape, but this study suggests that HRT may be a valuable tool for managing the shifting sands of body composition. It offers a glimmer of hope for maintaining health and well-being during this transitional phase.

Date :
  1. Date Completed 2000-05-01
  2. Date Revised 2019-07-09
Further Info :

Pubmed ID

10495407

DOI: Digital Object Identifier

10.1677/joe.0.1630055

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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