Additional methadone increases craving for heroin: a double-blind, placebo-controlled study of chronic opiate users receiving methadone substitution treatment.

Author: BoltonJ, CurranH V, SmythC, WanigaratneS

Paper Details 
Original Abstract of the Article :
AIMS: To assess the acute-on-chronic effects of methadone on drug craving, mood and cognitive and psychomotor functioning in patients on long-term methadone substitution treatment. DESIGN AND PARTICIPANTS: A double-blind, cross-over design was used to compare the effects of a 33% increase in patien...See full text at original site
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引用元:
https://doi.org/10.1046/j.1360-0443.1999.9456654.x

データ提供:米国国立医学図書館(NLM)

Methadone and Heroin Craving: Navigating the Desert of Addiction

The desert of addiction is a treacherous landscape, where cravings for drugs can be a relentless force, like a sandstorm that threatens to engulf the traveler. Researchers are constantly searching for ways to help those struggling with addiction, exploring the complexities of medication-assisted treatment, like seeking a safe passage through this unforgiving terrain. This study examines the effects of methadone, a medication used to treat opioid addiction, on heroin cravings in individuals receiving methadone substitution therapy.

The authors meticulously analyze the data from a double-blind, placebo-controlled study, seeking to understand the impact of methadone on cravings, mood, and cognitive function. Their findings reveal a surprising and concerning outcome: additional methadone significantly increased both positive and negative cravings for heroin. This unexpected discovery, like stumbling upon a hidden danger in the desert, highlights the complexities of addiction and the need for careful consideration of treatment strategies.

A Shifting Landscape: The Complexities of Addiction Treatment

The authors' findings challenge the conventional view of methadone as a simple solution for heroin addiction. They suggest that methadone, while effective in reducing withdrawal symptoms, may also inadvertently increase cravings, potentially hindering the journey to recovery. This is like discovering a hidden oasis that turns out to be a mirage, a deceptive illusion that masks the true dangers of the desert.

Dr. Camel's Conclusion

The desert of addiction is a place of constant change, where the landscape shifts and the dangers are often hidden from view. This study reminds us that addiction is a complex and multifaceted disease, requiring careful navigation and tailored treatment strategies. The authors' findings, like a warning sign in the desert, highlight the importance of understanding the potential risks and benefits of medication-assisted treatment. We must be ever vigilant in our search for solutions to this challenging problem.

Date :
  1. Date Completed 1999-11-24
  2. Date Revised 2019-09-15
Further Info :

Pubmed ID

10563031

DOI: Digital Object Identifier

10.1046/j.1360-0443.1999.9456654.x

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