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The effects of six months of treatment with a low-dose of conjugated oestrogens in menopausal women.
Author: EbertC, JunkerR, PetersdorfL I, SchlegelW, SchulteH, Von EckardsteinA
Original Abstract of the Article :
OBJECTIVE: Hormone replacement therapy (HRT) is usually prescribed as medium- to high-dose formulations. Little is known, however, about dose-dependency of oestrogen effects on plasma hormone levels, markers of cardiovascular risk in lipid metabolism and the haemostatic system, or markers of bone tu...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1046/j.1365-2265.1999.00857.x
データ提供:米国国立医学図書館(NLM)
Hormone Replacement Therapy: Finding the Right Dose
Hormone replacement therapy (HRT) is a common treatment for menopausal women, often compared to a refreshing oasis in the desert of aging. But like a desert landscape, finding the right dose can be tricky. This study investigated the effects of different doses of conjugated oestrogens (CEE) on various markers in menopausal women. It's like trying to find the perfect balance of water and shade in the desert, ensuring optimal comfort and well-being.
Lower Doses of CEE: A Potential Advantage
The researchers found that a low dose of CEE (0.3 mg/day) effectively lowered cholesterol levels without causing the adverse effects seen with higher doses. It's like discovering a small, hidden oasis, providing just the right amount of hydration without overwhelming the traveler. However, this low dose did not produce the maximum cholesterol-lowering effect. The findings suggest that lower doses may offer a valuable option for some patients.
Navigating the Desert of HRT
This research highlights the importance of finding the right dose of HRT for individual patients. It's like a camel caravan adjusting its pace and supplies based on the specific terrain and resources. Further research is needed to determine the optimal dose for various health outcomes, including cardiovascular risk and bone turnover.
Dr. Camel's Conclusion
Hormone replacement therapy, like a desert oasis, can provide relief and support for menopausal women. This research underscores the need for individualized treatment plans, carefully considering the specific needs and responses of each patient. Like a patient camel traversing a desert, finding the right dose can make all the difference in the journey to health and well-being.
Date :
- Date Completed 2000-04-11
- Date Revised 2019-08-13
Further Info :
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