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Combination phototherapy of psoriasis with narrow-band UVB irradiation and topical tazarotene gel.

Author: BehrensS, Grundmann-KollmannM, KerscherM, PeterR U, SchienerR

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Narrow-band UVB phototherapy, with a wavelength specifically targeted for psoriasis, has significantly improved treatment outcomes. While topical treatments for psoriasis have limitations, tazarotene has proven effective for plaque-type psoriasis. Combining narrow-band UVB with topical agents, such as tazarotene, has been shown to enhance the effectiveness of both treatment approaches.
Paper Details　
Original Abstract of the Article :
Narrow-band UVB (311 nm) phototherapy offering an emission spectrum closely conforming to the peak of the action spectrum for clearing psoriasis has significantly improved phototherapy for psoriasis. Because the majority of the commonly used topical therapies in treatment of psoriasis have limitatio...See full text at original site
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引用元：
https://doi.org/10.1016/s0190-9622(00)90225-1

データ提供：米国国立医学図書館（NLM）

Combination Therapy for Psoriasis: Narrow-Band UVB and Topical Tazarotene

Psoriasis, a chronic skin condition characterized by itchy, scaly patches, can be a frustrating journey for those affected. This research explores the potential of combining narrow-band UVB phototherapy, which precisely targets the specific wavelengths responsible for psoriasis clearing, with topical tazarotene, a new agent offering a promising alternative to existing therapies.

Enhancing Efficacy with Combined Therapy

The study highlights the limitations of commonly used topical treatments for psoriasis, paving the way for novel approaches like tazarotene. The researchers investigated the benefits of combining narrow-band UVB with topical agents, finding that this combination could enhance the efficacy of both treatment modalities. Think of it like harnessing the power of the desert sun to accelerate the healing process, while simultaneously applying a soothing balm to alleviate discomfort.

Potential for Improved Psoriasis Management

This study offers hope for patients with psoriasis by suggesting that a combination of narrow-band UVB and topical tazarotene could lead to more effective treatment outcomes. It's crucial to consult with a dermatologist to determine the appropriate treatment plan for each individual, considering the severity of their psoriasis, potential side effects, and overall health.

Dr.Camel's Conclusion

Combining narrow-band UVB with topical tazarotene for psoriasis treatment is like blending the warmth of the desert sun with a nourishing oasis, potentially leading to enhanced healing and improved outcomes. This study encourages further research into combination therapies to develop more effective and personalized treatment options for those living with this challenging skin condition.

Date :
  1. Date Completed 2000-03-29
  2. Date Revised 2021-04-09
Further Info :

Pubmed ID

10688723

DOI: Digital Object Identifier

10.1016/s0190-9622(00)90225-1

Related Literature

Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

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