The cutaneous side-effects of hydroxyurea.

Author: CoulsonI H, KendraJ R, KhanA S, YoungH S

Paper Details 
Original Abstract of the Article :
The cutaneous side-effects of long-term hydroxyurea therapy are not widely known and only rarely reported. We report on a patient who developed widespread skin changes, including the recently recognized hydroxyurea dermopathy, during long-term treatment with hydroxyurea for polycythaemia rubra vera....See full text at original site
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引用元:
https://doi.org/10.1046/j.1365-2257.2000.00311.x

データ提供:米国国立医学図書館(NLM)

The Skin-Deep Side Effects of Hydroxyurea

The [dermatological] side effects of long-term [hydroxyurea therapy] are often overlooked, and this study sheds light on this important topic. The authors present a case of [a patient who developed widespread skin changes, including hydroxyurea dermopathy] during long-term treatment for [polycythemia rubra vera]. This case highlights the need for increased [clinical awareness] of this potential complication. The study suggests that these skin changes may result from [direct toxicity of hydroxyurea on the basal layer of the epidermis and mucosal surfaces].

Recognizing the Signs of Toxicity

This case study serves as a stark reminder that [long-term medications can have unexpected side effects], even those that are widely used. The study emphasizes the importance of [monitoring for potential skin changes] in patients undergoing [hydroxyurea therapy]. Early recognition of these changes can facilitate [timely intervention] and help minimize the potential for [adverse outcomes].

Navigating the Skin's Desert

Imagine the harsh desert sun, relentless and unforgiving. Just as the sun can cause severe skin damage, certain medications like hydroxyurea can also have significant skin-related side effects. This case study serves as a guide to help us navigate the potential challenges of [long-term medication use], ensuring that we provide our patients with the best possible care and minimize the risk of unexpected complications.

Dr.Camel's Conclusion

This case study reminds us that even common medications can have surprising side effects, highlighting the importance of careful monitoring and vigilance in patient care. Understanding the potential for skin changes associated with hydroxyurea therapy can help us better manage the treatment of polycythemia rubra vera, ensuring the safety and well-being of our patients.

Date :
  1. Date Completed 2000-11-29
  2. Date Revised 2019-09-21
Further Info :

Pubmed ID

11012636

DOI: Digital Object Identifier

10.1046/j.1365-2257.2000.00311.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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