Hemodynamic effects of epoprostenol in patients with systemic sclerosis and pulmonary hypertension.

Author: BolsterM, GossageJ R, MazurJ, SilverR, StrangeC, TaylorM

Paper Details 
Original Abstract of the Article :
STUDY OBJECTIVES: To determine the cause of pulmonary hypertension (PH) in systemic sclerosis (SSc) patients since PH can occur because of pulmonary arteriopathy, pulmonary parenchymal destruction, and left ventricular cardiac dysfunction. DESIGN AND SETTING: Consecutive case series in a university...See full text at original site
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引用元:
https://doi.org/10.1378/chest.118.4.1077

データ提供:米国国立医学図書館(NLM)

Epoprostenol: A Potential Oasis for Pulmonary Hypertension in Systemic Sclerosis

Systemic sclerosis, a debilitating autoimmune disease, often leads to pulmonary hypertension (PH), a condition that puts significant strain on the heart and lungs. The complex interplay between systemic sclerosis and PH can make treatment challenging, creating a desert of uncertainty for patients. This study investigates the effects of epoprostenol, a medication that dilates blood vessels, on patients with systemic sclerosis and pulmonary hypertension, seeking to uncover a potential oasis of relief in this difficult landscape.

The authors conducted a case series study, evaluating the acute hemodynamic effects of epoprostenol infusion in patients with systemic sclerosis and PH. The study found that epoprostenol effectively reduced pulmonary vascular resistance in most patients, suggesting that it could provide a valuable tool for managing PH in this challenging patient population.

A Potential Oasis in the Desert of Systemic Sclerosis

The study's findings suggest that epoprostenol may offer a potential oasis of relief for patients with systemic sclerosis and pulmonary hypertension, providing a much-needed ray of hope in this difficult landscape. This discovery could lead to new strategies for managing PH in this complex and often debilitating condition.

Navigating the Desert of Systemic Sclerosis and Pulmonary Hypertension

This research offers a glimmer of hope for individuals battling the complex and challenging combination of systemic sclerosis and pulmonary hypertension. Epoprostenol may be a potential oasis of relief, providing a path toward improved blood flow and reduced symptoms. This research encourages further investigation into the use of epoprostenol for this challenging condition.

Dr.Camel's Conclusion

The desert of systemic sclerosis and pulmonary hypertension is a challenging and often unforgiving landscape. This study offers a glimmer of hope, suggesting that epoprostenol may be a potential oasis of relief for patients struggling with this complex condition. This research underscores the importance of seeking innovative solutions for managing challenging diseases and finding pathways towards improved health.

Date :
  1. Date Completed 2000-11-15
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

11035680

DOI: Digital Object Identifier

10.1378/chest.118.4.1077

Related Literature

SNS
PICO Info
in preparation
Languages

English

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