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The advanced glaucoma intervention study, 6: effect of cataract on visual field and visual acuity. The AGIS Investigators.

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Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Cataract surgery improved visual acuity and visual field defect scores in patients with advanced glaucoma. The study involved 332 black patients and 249 white patients who participated in the Advanced Glaucoma Intervention Study (AGIS). Adjustments for cataract reduced the race-treatment interaction observed in the study, but did not alter the conclusion that different treatment sequences are recommended for black and white patients.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To investigate the effect of cataract on visual function and the role of cataract in explaining a race-treatment interaction in outcomes of glaucoma surgery. METHODS: The Advanced Glaucoma Intervention Study (AGIS) enrolled 332 black patients (451 eyes) and 249 white patients (325 eyes) ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1001/archopht.118.12.1639

データ提供：米国国立医学図書館（NLM）

Cataract's Impact on Glaucoma Treatment: A Deeper Look

Glaucoma, a serious eye disease that can lead to blindness, requires careful management to preserve vision. This study investigates the impact of cataract on visual function and the potential influence of cataract on the effectiveness of glaucoma surgery. The researchers analyzed data from the Advanced Glaucoma Intervention Study (AGIS), a large clinical trial that compared different surgical approaches for glaucoma.

A Complex Picture: Cataract and Glaucoma Treatment

The study found that cataract surgery improved visual acuity and visual field scores, particularly in patients with poorer preoperative visual acuity. Adjusting for the effects of cataract on visual function revealed that the race-treatment interaction observed in the AGIS trial, which suggested different treatment strategies for black and white patients, was partially explained by the prevalence of cataract. These findings highlight the importance of considering the presence of cataract when evaluating the outcomes of glaucoma surgery.

Maintaining Clear Vision: Navigating the Desert of Eye Health

Glaucoma and cataract are common eye conditions that require careful management to preserve vision. If you have any concerns about your eye health, it's essential to consult with an ophthalmologist for a comprehensive evaluation. Regular eye exams and proactive management can help us navigate the vast and often challenging desert of eye health and maintain clear vision for a lifetime.

Dr.Camel's Conclusion

This study emphasizes the importance of considering multiple factors, including the presence of cataract, when evaluating the outcomes of glaucoma surgery. It underscores the need for comprehensive assessments and individualized treatment approaches to ensure the best possible outcomes for patients with glaucoma. This research serves as a valuable reminder that our journey to preserve vision requires a multifaceted approach, taking into account the complex interplay of various eye conditions.

Date :
  1. Date Completed 2000-12-22
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

11115258

DOI: Digital Object Identifier

10.1001/archopht.118.12.1639

Related Literature

Article Analysis
・Effective treatment of cataract
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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