Paper Details

  1. Home
  2. Paper Details

Is primaquine useful and safe as true exo-erythrocytic merontocidal, hypnozoitocidal and gametocidal antimalarial drug?

Author: López-AntuñanoF J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Primaquine, an antimalarial drug, is effective against P. vivax gametocytes and may prevent relapses. However, the drug's use is limited by its potential for hemolytic and methemoglobinemic side effects, especially in individuals with glucose-6-phosphate dehydrogenase deficiency.
Paper Details　
Original Abstract of the Article :
The main objective of this paper is to make available in a single document, a sequence of events that have been published on the biology of malaria parasites and their interaction with the human host, looking for arguments for effective and save treatment: what we know and what we would like to know...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1590/s0036-36341999000500010

データ提供：米国国立医学図書館（NLM）

Primaquine: A Controversial Antimalarial Drug

Malaria is a serious disease, a desert storm that can be deadly. This study delves into the use of primaquine, an antimalarial drug, and explores its complex role in treating and preventing malaria. The researchers examine the efficacy and safety of primaquine, discussing its potential benefits and risks, and highlight the importance of understanding its effects on different stages of the malaria parasite.

Primaquine: A Versatile but Complex Drug

The study highlights the unique properties of primaquine, its ability to eliminate different stages of the malaria parasite, including hypnozoites, the dormant forms of the parasite responsible for relapses. However, the study also emphasizes the importance of considering the drug's potential side effects, particularly in patients with glucose-6-phosphate dehydrogenase deficiency.

Navigating the Desert of Malaria Treatment

This study underscores the importance of careful consideration when prescribing primaquine, weighing its potential benefits against its risks. The study reminds us that the desert of malaria treatment is complex and requires a nuanced approach to ensure optimal patient care.

Dr.Camel's Conclusion

This study provides a comprehensive overview of the use of primaquine in treating and preventing malaria. The study highlights the complex role of primaquine and emphasizes the importance of considering its potential benefits and risks. It reminds us that the desert of malaria treatment requires a nuanced approach to ensure optimal patient care.

Date :
  1. Date Completed 2001-01-04
  2. Date Revised 2019-10-25
Further Info :

Pubmed ID

11142837

DOI: Digital Object Identifier

10.1590/s0036-36341999000500010

Related Literature

Article Analysis
・Side Effects of primaquine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.