Ischemic colitis during treatment with alosetron.

Author: FisherR S, FriedelD, ThomasR

Paper Details 
Original Abstract of the Article :
Irritable bowel syndrome (IBS) is one of the most common entities observed by both primary care physicians and gastroenterologists. Alosetron is a potent and selective serotonin antagonist that recently became the first Food and Drug Administration-approved agent for diarrhea-predominant IBS. Howeve...See full text at original site
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引用元:
https://doi.org/10.1053/gast.2001.21177

データ提供:米国国立医学図書館(NLM)

Alosetron and the Risk of Ischemic Colitis

Irritable bowel syndrome (IBS) is a common digestive disorder that can significantly impact an individual's quality of life. This research explores the potential risks associated with the use of alosetron, a drug approved for diarrhea-predominant IBS. The study presents a case report of a male patient who developed ischemic colitis after being treated with alosetron. The authors meticulously analyze the patient's clinical, endoscopic, and pathologic findings, highlighting the temporal correlation between alosetron use and the development of ischemic colitis.

The Potential Risks of Alosetron

The research underscores the potential risks associated with the use of alosetron, particularly in the context of ischemic colitis. The case report highlights the need for careful monitoring and a thorough understanding of the drug's potential side effects. The authors emphasize that alosetron should be used with caution, particularly in patients at increased risk for ischemic colitis. This research sheds light on the importance of balancing the benefits and risks of medications, particularly those used for managing chronic conditions like IBS.

Managing Irritable Bowel Syndrome

Patients with IBS should consult with their healthcare providers to discuss the risks and benefits of different treatment options, including alosetron. The decision should be made on a case-by-case basis, taking into account the patient's individual medical history, risk factors, and overall health.

Dr. Camel's Conclusion

This research provides a valuable reminder that even seemingly safe medications can have unexpected side effects. It highlights the importance of careful monitoring and a thorough understanding of potential risks when prescribing medications. It's like navigating a desert landscape, where every step must be carefully considered to avoid hidden dangers.

Date :
  1. Date Completed 2001-03-29
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

11159896

DOI: Digital Object Identifier

10.1053/gast.2001.21177

Related Literature

SNS
PICO Info
in preparation
Languages

English

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