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Original Abstract of the Article :
Irritable bowel syndrome (IBS) is one of the most common entities observed by both primary care physicians and gastroenterologists. Alosetron is a potent and selective serotonin antagonist that recently became the first Food and Drug Administration-approved agent for diarrhea-predominant IBS. Howeve...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1053/gast.2001.21177
データ提供:米国国立医学図書館(NLM)
Alosetron and the Risk of Ischemic Colitis
Irritable bowel syndrome (IBS) is a common digestive disorder that can significantly impact an individual's quality of life. This research explores the potential risks associated with the use of alosetron, a drug approved for diarrhea-predominant IBS. The study presents a case report of a male patient who developed ischemic colitis after being treated with alosetron. The authors meticulously analyze the patient's clinical, endoscopic, and pathologic findings, highlighting the temporal correlation between alosetron use and the development of ischemic colitis.
The Potential Risks of Alosetron
The research underscores the potential risks associated with the use of alosetron, particularly in the context of ischemic colitis. The case report highlights the need for careful monitoring and a thorough understanding of the drug's potential side effects. The authors emphasize that alosetron should be used with caution, particularly in patients at increased risk for ischemic colitis. This research sheds light on the importance of balancing the benefits and risks of medications, particularly those used for managing chronic conditions like IBS.
Managing Irritable Bowel Syndrome
Patients with IBS should consult with their healthcare providers to discuss the risks and benefits of different treatment options, including alosetron. The decision should be made on a case-by-case basis, taking into account the patient's individual medical history, risk factors, and overall health.
Dr. Camel's Conclusion
This research provides a valuable reminder that even seemingly safe medications can have unexpected side effects. It highlights the importance of careful monitoring and a thorough understanding of potential risks when prescribing medications. It's like navigating a desert landscape, where every step must be carefully considered to avoid hidden dangers.
Date :
- Date Completed 2001-03-29
- Date Revised 2022-03-17
Further Info :
Related Literature
English
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