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Pharmacological treatment of severe hypertension in pregnancy and the role of serotonin(2)-receptor blockers.

Author: BolteA C, DekkerG A, van GeijnH P

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Ketanserin, a serotonin(2)-receptor blocker, is a promising drug for treating pregnancy-induced hypertensive disorders.
Paper Details　
Original Abstract of the Article :
Hypertensive disorders of pregnancy are the leading cause of maternal and perinatal mortality and morbidity in developing and developed countries. The etiology of preeclampsia is still unknown. Delivering the baby is the only definite treatment. The benefits of acute pharmacological control of sever...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1016/s0301-2115(00)00368-7

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Pregnancy-Induced Hypertension: The Role of Serotonin(2)-Receptor Blockers

The [management of severe hypertension in pregnancy] is a complex and challenging area of medicine. This review discusses the [pharmacological treatment] of [severe hypertension in pregnancy] and the role of [serotonin(2)-receptor blockers]. The author highlights the [challenges] of [treating preeclampsia], a condition characterized by [endothelial cell dysfunction, vasospasm, and platelet aggregation]. While [most commonly used antihypertensive drugs] have [significant maternal and/or neonatal adverse side effects], [ketanserin], a [serotonin(2)-receptor blocker], appears to be [tailored to the pathophysiology of preeclampsia]. The author summarizes the [existing experience] with [ketanserin] and concludes that [serotonin(2)-receptor blockers] may have a [definite place] in the [treatment of pregnancy-induced hypertensive disorders].

Ketanserin: A Desert Oasis for Preeclampsia

This review, like a well-traveled guide through the desert of pregnancy-induced hypertension, highlights the potential of serotonin(2)-receptor blockers, particularly ketanserin, as a therapeutic option for preeclampsia.

A Brighter Path for Pregnant Women: Exploring New Treatment Options

This research encourages continued exploration of [new and innovative treatment options] for [pregnancy-induced hypertension]. By seeking [safer and more effective therapies], we can improve the [health outcomes] of both [mothers and their babies].

Dr.Camel's Conclusion

This review, like a caravan navigating the harsh terrain of pregnancy-induced hypertension, offers hope for a safer and more effective treatment approach. Ketanserin, like a desert oasis, provides a potential solution for this complex condition, ensuring a healthier journey for pregnant women.

Date :
  1. Date Completed 2001-07-12
  2. Date Revised 2019-08-16
Further Info :

Pubmed ID

11267716

DOI: Digital Object Identifier

10.1016/s0301-2115(00)00368-7

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English

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