Effects of ceramic component on cephalexin release from bioactive bone cement consisting of Bis-GMA/TEGDMA resin and bioactive glass ceramics.

Author: FujitaH, KokuboT, NakamuraT, OtsukaM

Paper Details 
Original Abstract of the Article :
The purpose of this study was to elucidate the effect of amount of ceramic cement powder on drug release from bioactive bone cement. The associated bone-bonding strength was also investigated. The bioactive bone cement under investigation consisted of bisphenol-alpha-glycidyl methacrylate (Bis-GMA),...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/11281575

データ提供:米国国立医学図書館(NLM)

Unveiling the Secrets of Bioactive Bone Cement

This study delves into the intriguing world of biomaterials, specifically investigating the role of ceramic components in bioactive bone cement. Bioactive bone cement is like a magical concoction that can be used to repair damaged bones. The key ingredient in this magical mixture is a combination of bisphenol-alpha-glycidyl methacrylate (Bis-GMA), triethylene-glycol dimethacrylate (TEGDMA) resin, and bioactive glass ceramics. The researchers are trying to figure out how changing the amount of ceramic powder in the mixture affects the release of a drug called cephalexin and the strength of the bone cement. They found that increasing the amount of ceramic powder led to a stronger cement that bonded better with bone. This is like a strong camel caravan that carries the heavy load of repairing broken bones. It also increased the rate at which the drug was released, demonstrating the versatility of this material.

Unlocking the Potential of Bioactive Bone Cement

The study reveals that the compressive strength of the cement with 80% ceramic powder was 194 MPa, three times higher than that of conventional polymethylmethacrylate cement. This finding is like finding a hidden oasis in the desert, offering a promising solution for repairing broken bones.

A New Era in Bone Repair

This research provides exciting insights into the potential of bioactive bone cement as a powerful tool in bone repair. This new technology could one day help to heal broken bones faster and more effectively, offering hope to patients who have suffered injuries.

Dr.Camel's Conclusion

This study highlights the exciting potential of bioactive bone cement in the field of biomaterials. By understanding how to control the release of drugs and the strength of the cement, researchers are paving the way for new and innovative treatments for bone injuries. This is a journey of scientific discovery, and the future holds promise for even more breakthroughs in the desert of bone repair.

Date :
  1. Date Completed 2001-06-28
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

11281575

DOI: Digital Object Identifier

11281575

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English

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