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Ondansetron: a review of its use as an antiemetic in children.

Author: BhanaN, CulyC R, PloskerG L

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Ondansetron, a selective serotonin (5-HT) 5-HT3 receptor antagonist, is an antiemetic agent used in adults and children. Ondansetron has been shown to be effective in reducing nausea and vomiting in children receiving chemotherapy and undergoing surgery, with generally good tolerability.
Paper Details　
Original Abstract of the Article :
Ondansetron, a selective serotonin (5-hydroxytryptamine; 5-HT) 5-HT3 receptor antagonist, is an antiemetic agent available for use in adults and children. In children receiving ondansetron (multiple 5 mg/m2 or 0.15 mg/kg intravenous and/or oral doses) in addition to chemotherapy in 2 large (n > 100)...See full text at original site
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引用元：
https://doi.org/10.2165/00128072-200103060-00007

データ提供：米国国立医学図書館（NLM）

Ondansetron: A Review of Its Use as an Antiemetic in Children

Children undergoing medical procedures can experience significant discomfort, and nausea and vomiting are common side effects. This study reviews the use of ondansetron, a medication known for its antiemetic properties, in children. The authors explore ondansetron's efficacy in preventing and treating nausea and vomiting in various settings, including chemotherapy and surgery.

A Cool Oasis in the Desert of Nausea and Vomiting

The study found that ondansetron was effective in reducing nausea and vomiting in children receiving chemotherapy, surgery, or undergoing bone marrow transplantation. The authors also highlight the importance of combining ondansetron with other antiemetics, such as dexamethasone, to further enhance its effectiveness.

Finding the Right Path Through the Desert

This research provides valuable information for clinicians managing nausea and vomiting in children. The study's findings suggest that ondansetron can be a safe and effective antiemetic for children in a range of medical settings, improving their comfort and quality of care.

Dr.Camel's Conclusion

This research offers a comprehensive overview of the use of ondansetron as an antiemetic in children. The study's findings highlight the efficacy and safety of ondansetron in various settings, providing valuable insights for clinicians seeking to alleviate nausea and vomiting in children. It's like discovering a cool oasis in the desert of nausea and vomiting, offering relief and comfort for young patients undergoing medical procedures.

Date :
  1. Date Completed 2001-12-28
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

11437189

DOI: Digital Object Identifier

10.2165/00128072-200103060-00007

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