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Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.

Author: FaulknerM, HillemanD E, ReyesA P, WurdemanR L

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This review article discusses the importance of achieving goal blood pressures in patients with hypertension. Fixed-dose combination products may be useful in reducing the number of daily doses required to control blood pressure.
Paper Details　
Original Abstract of the Article :
Recent hypertension trials have demonstrated the importance of achieving goal blood pressures to reduce the risk of target organ damage. In patients with moderate to severe hypertension, the use of high-dose monotherapy and/or combinations of drugs are necessary to achieve these goals. Fixed-dose co...See full text at original site
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引用元：
https://doi.org/10.1038/sj.jhh.1001230

データ提供：米国国立医学図書館（NLM）

The Great Blood Pressure Chase: A Combination Approach to Tame Hypertension

High blood pressure, like a relentless camel caravan on the move, can wreak havoc on your body. This research explores the efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension. The goal? To keep blood pressure under control and prevent the damage that hypertension can cause. The researchers examined the potential benefits of a combination approach, which involves switching from a single high-dose medication to a fixed-dose combination therapy.

Fixed-Dose Combinations: A Strategic Alliance for Blood Pressure Control

The study found that the fixed-dose combination of amlodipine/benazepril was effective in managing blood pressure and reducing the number of daily doses required to achieve blood pressure goals. This combination approach may provide a more convenient and effective way to manage hypertension in individuals with moderate-to-severe hypertension.

A Combined Effort for a Healthier Heart

This research underscores the importance of effective blood pressure management in preventing cardiovascular disease. It suggests that a combination therapy approach may provide a more efficient and manageable way to control blood pressure, reducing the risk of complications and improving overall cardiovascular health.

Dr. Camel's Conclusion

This study provides further evidence for the benefits of using fixed-dose combination therapies to manage hypertension. It emphasizes the importance of considering the potential benefits of a combination approach in the fight against this widespread and often silent health issue.
Date :
  1. Date Completed 2001-10-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

11494095

DOI: Digital Object Identifier

10.1038/sj.jhh.1001230

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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