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Double-blind randomized trial of mifepristone in combination with vaginal gemeprost or misoprostol for induction of abortion up to 63 days gestation.
Author: BairdD T, BartleyJ, BrownA, EltonR
Original Abstract of the Article :
BACKGROUND: Gemeprost and misoprostol are two of the most widely used prostaglandins in combination with mifepristone for medical abortion in early pregnancy. However, the efficacy and side-effects of those two drugs given vaginally have not been assessed in a randomized trial. METHODS: Randomized ...See full text at original site
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引用元:
https://doi.org/10.1093/humrep/16.10.2098
データ提供:米国国立医学図書館(NLM)
Mifepristone and Prostaglandins for Medical Abortion: A Randomized Trial
Medical abortion, a safe and effective option for early pregnancy termination, has become increasingly common. This double-blind randomized trial compares the efficacy and safety of two different prostaglandins, gemeprost and misoprostol, in combination with mifepristone for medical abortion. It's like comparing two different paths across a vast desert, seeking the most efficient and safe route to a desired destination.
Two Paths to a Desired Destination: A Comparative Study
The researchers found that both gemeprost and misoprostol, when used in combination with mifepristone, were highly effective in inducing abortion. However, misoprostol was associated with a significantly higher rate of complete abortion and fewer ongoing pregnancies. It's like choosing a path with a slightly longer distance but a smoother and more reliable journey.
Navigating the Choices in Medical Abortion
This research provides valuable information for clinicians and patients considering medical abortion. It highlights the importance of selecting the most appropriate prostaglandin based on individual factors and clinical considerations. Just as a camel chooses the optimal path based on the terrain and its own capabilities, clinicians must consider the unique needs of each patient in selecting the most effective treatment option.
Dr.Camel's Conclusion
This randomized trial provides valuable evidence for the efficacy and safety of both gemeprost and misoprostol in combination with mifepristone for medical abortion. It highlights the importance of individualizing treatment choices based on patient factors and clinical considerations. Just as a camel chooses the most appropriate path across the desert, clinicians must navigate the complex landscape of medical abortion with care and precision.
Date :
- Date Completed 2001-12-04
- Date Revised 2019-05-13
Further Info :
Related Literature
English
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