Double-blind randomized trial of mifepristone in combination with vaginal gemeprost or misoprostol for induction of abortion up to 63 days gestation.

Author: BairdD T, BartleyJ, BrownA, EltonR

Paper Details 
Original Abstract of the Article :
BACKGROUND: Gemeprost and misoprostol are two of the most widely used prostaglandins in combination with mifepristone for medical abortion in early pregnancy. However, the efficacy and side-effects of those two drugs given vaginally have not been assessed in a randomized trial. METHODS: Randomized ...See full text at original site
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引用元:
https://doi.org/10.1093/humrep/16.10.2098

データ提供:米国国立医学図書館(NLM)

Mifepristone and Prostaglandins for Medical Abortion: A Randomized Trial

Medical abortion, a safe and effective option for early pregnancy termination, has become increasingly common. This double-blind randomized trial compares the efficacy and safety of two different prostaglandins, gemeprost and misoprostol, in combination with mifepristone for medical abortion. It's like comparing two different paths across a vast desert, seeking the most efficient and safe route to a desired destination.

Two Paths to a Desired Destination: A Comparative Study

The researchers found that both gemeprost and misoprostol, when used in combination with mifepristone, were highly effective in inducing abortion. However, misoprostol was associated with a significantly higher rate of complete abortion and fewer ongoing pregnancies. It's like choosing a path with a slightly longer distance but a smoother and more reliable journey.

Navigating the Choices in Medical Abortion

This research provides valuable information for clinicians and patients considering medical abortion. It highlights the importance of selecting the most appropriate prostaglandin based on individual factors and clinical considerations. Just as a camel chooses the optimal path based on the terrain and its own capabilities, clinicians must consider the unique needs of each patient in selecting the most effective treatment option.

Dr.Camel's Conclusion

This randomized trial provides valuable evidence for the efficacy and safety of both gemeprost and misoprostol in combination with mifepristone for medical abortion. It highlights the importance of individualizing treatment choices based on patient factors and clinical considerations. Just as a camel chooses the most appropriate path across the desert, clinicians must navigate the complex landscape of medical abortion with care and precision.

Date :
  1. Date Completed 2001-12-04
  2. Date Revised 2019-05-13
Further Info :

Pubmed ID

11574498

DOI: Digital Object Identifier

10.1093/humrep/16.10.2098

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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