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[Antilymphocyte globulin combining with cyclosporine A in the treatment of severe aplastic anemia].

Author: ChuY, ShaoZ, ZhengY

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Intensive immunosuppressive therapy (IIST) with antilymphocyte globulin (ALG) and cyclosporine A (CsA) had a higher response rate (83.7%) for severe aplastic anemia (SAA) than non-intensive immunosuppressive therapy (NIIST) with ALG alone (57.6%). IIST also resulted in a lower risk of early mortality and a shorter time to red cell transfusion independence.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To explore more effective regimen for severe aplastic anemia (SAA). METHODS: A prospective, randomized clinical trial was conducted to determine whether the outcome of SAA patients treated with the combination of antilymphocyte globulin(ALG) and cyclosporine A(CsA) (intensive immunosuppr...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/11601221

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 2001-12-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

11601221

DOI: Digital Object Identifier

11601221

SNS
PICO Info
in preparation
Languages

Chinese

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