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Ciprofloxacin microprecipitates and macroprecipitates in the human corneal epithelium.

Author: EifermanR A, NordquistR E, SnyderJ P

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

This study reports on the development of ciprofloxacin micro- and macroprecipitates in corneal transplant patients treated preoperatively with ciprofloxacin ophthalmic drops. The precipitates were found to be pure ciprofloxacin and bioactive in vitro.
Paper Details　
Original Abstract of the Article :
In 4 corneal transplantation patients treated preoperatively with ciprofloxacin ophthalmic drops, microprecipitates associated with damaged corneal epithelium were noted in 2 patients. Another patient developed a large macroprecipitate in a corneal ulcer. All specimens were examined by electron micr...See full text at original site
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引用元：
https://doi.org/10.1016/s0886-3350(01)00893-8

データ提供：米国国立医学図書館（NLM）

Ciprofloxacin: A Double-Edged Sword in Corneal Health

This research explores the potential complications of using ciprofloxacin, an antibiotic often used to treat eye infections, in corneal transplantation patients. It's like examining a precious desert oasis, carefully assessing its potential benefits and risks. The study examined the formation of ciprofloxacin precipitates in the corneal epithelium, which could affect the healing process.

Precipitates: A Threat to Corneal Healing

The study found that ciprofloxacin can form precipitates in the cornea, potentially interfering with healing. It's like discovering that a seemingly life-giving oasis harbors hidden dangers. This discovery underscores the importance of monitoring patients closely for potential side effects.

Navigating the Eye Care Desert

This research emphasizes the importance of careful consideration when using ciprofloxacin in corneal transplantation patients. It's like learning to navigate a desert with both beauty and danger. Understanding the potential risks and benefits of this medication is crucial for ensuring optimal patient care.

Dr. Camel's Conclusion

This study reminds us that even seemingly simple solutions can have unexpected complexities. It's like discovering that a seemingly benign desert plant harbors a dangerous toxin. Understanding the intricacies of medication interactions and potential side effects is essential for responsible healthcare practice.

Date :
  1. Date Completed 2001-12-07
  2. Date Revised 2019-08-22
Further Info :

Pubmed ID

11687375

DOI: Digital Object Identifier

10.1016/s0886-3350(01)00893-8

Related Literature

Article Analysis
・Effects of ciprofloxacin ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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