Vitamin D analogues for the management of secondary hyperparathyroidism.

Author: GonzálezE A, MartinK J

Paper Details 
Original Abstract of the Article :
Secondary hyperparathyroidism complicating chronic kidney disease requires therapy to minimize the effects of parathyroid hormone (PTH) on bone and other tissues. Low levels of calcitriol in blood play a major role in the initiation and maintenance of hyperparathyroidism. Accordingly, administration...See full text at original site
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引用元:
https://doi.org/10.1053/ajkd.2001.28109

データ提供:米国国立医学図書館(NLM)

Vitamin D Analogs: A New Hope for Secondary Hyperparathyroidism

This review explores the use of [vitamin D analogs] in the management of [secondary hyperparathyroidism], a common complication of [chronic kidney disease]. The authors discuss the [challenges] of treating [secondary hyperparathyroidism] with [calcitriol] and highlight the [potential advantages] of [vitamin D analogs], such as [paricalcitol] and [doxercalciferol].

The review explains that [vitamin D analogs] can [effectively suppress parathyroid hormone (PTH)] with [lesser effects on calcium and phosphorus] in serum, thereby minimizing the undesirable [side effects] of traditional [vitamin D therapy]. This discovery is significant because it could lead to [improved treatment options] for [secondary hyperparathyroidism], reducing the risk of [complications] associated with [hypercalcemia] and [hyperphosphatemia].

Finding a Balance in Vitamin D Therapy

This review highlights the [benefits] of using [vitamin D analogs] to manage [secondary hyperparathyroidism]. It's like finding a delicate balance in the desert - using the right amount of water to nourish without causing flooding. The [selective activity] of [vitamin D analogs] allows for [more targeted treatment], reducing the risk of [adverse effects] associated with traditional [vitamin D therapy].

Navigating the Desert of Kidney Disease

This review provides valuable insights into the [management of secondary hyperparathyroidism] in [patients with chronic kidney disease]. It's like navigating a vast desert - understanding the landscape and its challenges is crucial for survival. The use of [vitamin D analogs] offers a [potential solution] to this [common complication] of [kidney disease], allowing patients to [manage their condition] and [improve their quality of life].

Dr.Camel's Conclusion

This review explores the use of vitamin D analogs in the management of secondary hyperparathyroidism, a common complication of chronic kidney disease. The authors discuss the challenges of treating secondary hyperparathyroidism with calcitriol and highlight the potential advantages of vitamin D analogs, such as paricalcitol and doxercalciferol. These analogs offer a more targeted approach to treatment, reducing the risk of adverse effects associated with traditional vitamin D therapy. This research represents a step forward in our understanding of vitamin D therapy and its application in managing kidney disease. It’s like finding a new oasis in the desert - a source of hope and relief for patients facing the challenges of chronic kidney disease.

Date :
  1. Date Completed 2001-12-04
  2. Date Revised 2019-08-15
Further Info :

Pubmed ID

11689385

DOI: Digital Object Identifier

10.1053/ajkd.2001.28109

Related Literature

SNS
PICO Info
in preparation
Languages

English

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