Paper Details 
Original Abstract of the Article :
Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Busulfan, with methanesulfonate leaving groups identical with those of Yoshi-864, is without effect. Tumor cells from mice bearing the Ehrlich tumor and treated with Yoshi-864 have a persistent...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元:
https://doi.org/10.3181/00379727-149-38751

データ提供:米国国立医学図書館(NLM)

Comparing the Effects of Yoshi-864 and Busulfan on Cancer Cells

The world of cancer research is a vast desert, with scientists tirelessly searching for oases of effective treatments. This study delves into the battle against cancer, specifically examining the effects of Yoshi-864 and busulfan on L1210 leukemia and Ehrlich ascites carcinoma. The study employed an experimental approach, using mice as models to investigate the effectiveness of these two drugs.

Yoshi-864: A Promising Oasis in the Cancer Desert

The results painted a clear picture. Yoshi-864 proved to be a potent weapon against both L1210 leukemia and Ehrlich ascites carcinoma, significantly extending the lifespan of the afflicted mice. Conversely, busulfan, despite sharing similar chemical properties with Yoshi-864, failed to show any meaningful effect. The researchers delved further, investigating the mechanism behind Yoshi-864's success. They found that Yoshi-864 effectively hindered the ability of tumor cells to replicate, by hindering their DNA synthesis.

Understanding DNA Synthesis: A Key to Cancer Treatment

DNA synthesis is the process by which cells create copies of their genetic material. This process is crucial for cell division and growth, and cancer cells rely heavily on it to proliferate. Yoshi-864's ability to disrupt this process is a significant finding. It could pave the way for the development of new and more effective treatments for cancer.

Dr. Camel's Conclusion

This study is a testament to the constant search for effective cancer treatments. While Yoshi-864 shows promising results, it's important to remember that cancer research is an ongoing journey. Further investigation is necessary to fully understand Yoshi-864's potential and to explore its application in human clinical settings.

Date :
  1. Date Completed 1975-09-29
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

1170570

DOI: Digital Object Identifier

10.3181/00379727-149-38751

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Languages

English

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