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The H1-receptor antagonist dextro-chlorpheniramine impairs selective auditory attention in the absence of subjective awareness of this impairment.

Author: EsceraC, GrauC, Sanchez-TuretM, Serra-GrabulosaJ M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the effects of chlorpheniramine on human auditory selective attention. Results showed that chlorpheniramine impaired auditory selective attention, as reflected by an attenuation of processing negativity amplitude and reduced performance in the dichotic listening task. This impairment was not accompanied by subjective changes in sleepiness, vigor, or affect, highlighting the potential for risk in tasks requiring auditory information.
Paper Details　
Original Abstract of the Article :
Although previous studies have shown that the human attention system is partially affected by chlorpheniramine, the effects of chlorpheniramine on human auditory selective attention have not yet been explored. This study examines the effects of a single dose of 4 mg of dextro-chlorpheniramine on hum...See full text at original site
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引用元：
https://doi.org/10.1097/00004714-200112000-00010

データ提供：米国国立医学図書館（NLM）

The Hidden Effects of Dextro-Chlorpheniramine on Auditory Attention

The world of medication can be filled with unexpected side effects. This research explores the impact of the antihistamine dextro-chlorpheniramine on selective auditory attention, a key cognitive function. The researchers conducted a double-blind study, administering dextro-chlorpheniramine or a placebo to participants while they performed an auditory attention task.

The Silent Sabotage of Attention

This study found that dextro-chlorpheniramine impaired selective auditory attention in participants, despite them not being aware of any changes in their cognitive abilities. This suggests that certain medications can have subtle but significant effects on cognitive function, potentially impacting daily activities.

Hidden Dangers in the Medicine Cabinet

This research highlights the importance of being aware of potential side effects of medications, even those that don't cause obvious changes in our awareness. It's crucial to consult with a healthcare professional about the potential risks and benefits of any medication, particularly those that can affect cognitive function.

Dr.Camel's Conclusion

Imagine a camel navigating a desert path, relying on its keen senses to avoid danger. Medications like dextro-chlorpheniramine can be like a silent mirage, subtly blurring our senses and potentially impacting our ability to navigate our surroundings. This research highlights the need for awareness and caution when using medications that could have unexpected effects on our cognitive function.

Date :
  1. Date Completed 2002-05-07
  2. Date Revised 2019-09-10
Further Info :

Pubmed ID

11763008

DOI: Digital Object Identifier

10.1097/00004714-200112000-00010

Related Literature

Article Analysis
・Side Effects of chlorpheniramine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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