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Marketed new antiepileptic drugs: are they better than old-generation agents?

Author: PeruccaEmilio

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This article discusses the impact of new-generation antiepileptic drugs on the management of epilepsy. While these drugs offer improved tolerability and efficacy, the need for more effective treatments and careful consideration of drug interactions remains.
Paper Details　
Original Abstract of the Article :
Until a decade ago, the pharmacologic armamentarium for the management of epilepsy was restricted to a little more than a handful of drugs that had been introduced 20 to 70 years earlier. This situation has changed dramatically, with as many as nine new-generation drugs (oxcarbazepine, gabapentin, l...See full text at original site
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引用元：
https://doi.org/10.1097/00007691-200202000-00013

データ提供：米国国立医学図書館（NLM）

New Antiepileptic Drugs: Are They Better?

The development of new antiepileptic drugs (AEDs) has revolutionized the management of epilepsy. This review article examines the efficacy and safety of newer-generation AEDs compared to older-generation agents.

The Advancement of Antiepileptic Therapy

The authors highlight the significant progress made in antiepileptic therapy with the introduction of newer drugs. While these newer AEDs offer improved tolerability, ease of use, and reduced interaction potential, their efficacy in truly refractory epilepsy may not be superior to older agents.

Considerations for Antiepileptic Drug Choice

This research underscores the importance of carefully considering the individual needs of patients with epilepsy when selecting AEDs. The authors emphasize the need for clinicians to have adequate knowledge of the indications, contraindications, and modes of use of newer AEDs to ensure optimal treatment and minimize potential risks.

Dr.Camel's Conclusion

This review provides a valuable overview of the evolving landscape of antiepileptic therapy, emphasizing the importance of balancing the benefits and risks of various AEDs. Like a camel searching for the best path through the desert, clinicians must navigate the complex world of epilepsy treatment with careful consideration of the individual needs of their patients.

Date :
  1. Date Completed 2002-04-23
  2. Date Revised 2019-09-06
Further Info :

Pubmed ID

11805726

DOI: Digital Object Identifier

10.1097/00007691-200202000-00013

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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