Use of recombinant human deoxyribonuclease (DNase) for processing of a thawed umbilical cord blood transplant in a patient with relapsed acute lymphoblastic leukemia.

Author: BeckC, BernardF, BugertP, EichlerH, KlüterH

Paper Details 
Original Abstract of the Article :
This case report describes for the first time the use of a recombinant human enzyme deoxyribonuclease (rhDNase) containing solution for the processing of a thawed umbilical cord blood (UCB) unit prior to successful transplantation to avoid cell losses by clotting phenomena. A 6-year-old boy received...See full text at original site
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引用元:
https://doi.org/10.1007/s00277-001-0419-2

データ提供:米国国立医学図書館(NLM)

A Rescue Mission in the Desert: Recombinant Human Deoxyribonuclease (rhDNase) for Umbilical Cord Blood Transplant

In the realm of leukemia treatment, finding the right path to recovery can be like searching for a life-giving oasis in a vast desert. This case report describes a novel approach using recombinant human deoxyribonuclease (rhDNase) to process a thawed umbilical cord blood (UCB) transplant for a patient with relapsed acute lymphoblastic leukemia. The researchers, like skilled camel caravan guides, navigate the complexities of UCB processing, introducing a new technique to ensure the successful transplantation of these precious cells. This innovative approach offers a glimmer of hope for patients facing leukemia, offering a potential pathway to recovery.

rhDNase: A Lifeline in the Desert of Leukemia Treatment

The successful use of rhDNase to process a thawed UCB unit, like a well-placed oasis in the desert of leukemia treatment, highlights the potential of this enzyme for improving transplant outcomes. This case report, like a beacon in the darkness, suggests that rhDNase could be a valuable tool for improving UCB transplantation and increasing the chances of successful recovery for patients.

Navigating the Desert of Leukemia: A Journey Towards Hope

This case report offers a glimpse into the evolving landscape of leukemia treatment. The use of rhDNase for UCB processing represents a promising development, offering a potential lifeline for patients seeking a cure. This research could lead to improved protocols for UCB transplantation, offering a more hopeful journey for patients battling this challenging disease.

Dr. Camel's Conclusion

This case report demonstrates the potential of rhDNase as a valuable tool for processing thawed UCB units for transplantation. The success of this approach, like a well-placed oasis in the desert of leukemia treatment, offers hope for patients seeking a cure. This innovative technique could lead to improved transplant outcomes, offering a brighter future for those facing this devastating disease.

Date :
  1. Date Completed 2002-06-06
  2. Date Revised 2007-11-15
Further Info :

Pubmed ID

11904746

DOI: Digital Object Identifier

10.1007/s00277-001-0419-2

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