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Different effects of tacrolimus and cyclosporine on renal hemodynamics and blood pressure in healthy subjects.
Author: AbrahamsAlferso, HenéRonald J, KleinInge H H T, KoomansHein A, LigtenbergGerry, van EdeThomas
Original Abstract of the Article :
The side effects of cyclosporine, nephrotoxicity and hypertension, contribute to long-term renal graft failure and cardiovascular morbidity in graft recipients. It is not clear whether tacrolimus is as nephrotoxic and hypertensive as cyclosporine. Data on this subject are not consistent because of d...See full text at original site
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引用元：
https://doi.org/10.1097/00007890-200203150-00012
データ提供：米国国立医学図書館（NLM）
Tacrolimus vs. Cyclosporine: Navigating the Desert of Immunosuppression
Immunosuppressant medications, like oases in the desert, are crucial for managing organ transplantation, but their use comes with potential side effects. This research compares the effects of tacrolimus and cyclosporine on renal hemodynamics and blood pressure in healthy subjects. The authors conducted a comparative study, exploring the potential differences in nephrotoxicity and hypertension associated with these two medications. The findings suggest that tacrolimus may be less nephrotoxic and hypertensive than cyclosporine, offering a potential advantage in managing organ transplant recipients.
Tacrolimus: A Potential Oasis in the Desert of Immunosuppression
The research findings suggest that tacrolimus may be a more favorable immunosuppressant option compared to cyclosporine, potentially offering a safer and more tolerable treatment option for organ transplant recipients. This discovery, like a refreshing oasis in the desert, offers hope for minimizing the side effects associated with immunosuppression.
Navigating the Desert of Immunosuppression: Tacrolimus Offers a Potential Advantage
Tacrolimus, like a well-charted path through the desert, may offer a more favorable option for managing immunosuppression compared to cyclosporine. This research underscores the importance of carefully considering the potential side effects of immunosuppressant medications and selecting the most appropriate treatment approach for individual patients.
Dr.Camel's Conclusion
This research compares the effects of tacrolimus and cyclosporine on renal hemodynamics and blood pressure in healthy subjects. The findings suggest that tacrolimus may be less nephrotoxic and hypertensive than cyclosporine, offering a potential advantage for managing organ transplant recipients. This research provides valuable insights into the comparative effects of immunosuppressant medications, guiding healthcare providers in selecting the most appropriate treatment approach for their patients.
Date :
- Date Completed 2002-04-11
- Date Revised 2019-07-13
Further Info :
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