Effects of selected anticholinergics on acoustic startle response in rats.

Author: BurchnellV, GalbickaG, SiposM L

Paper Details 
Original Abstract of the Article :
The present study compared the effects of the anticholinergics aprophen hydrochloride, atropine sulfate, azaprophen hydrochloride, benactyzine hydrochloride, biperiden hydrochloride, diazepam, procyclidine hydrochloride, scopolamine hydrobromide and trihexyphenidyl hydrochloride on acoustic startle ...See full text at original site
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引用元:
https://doi.org/10.1002/jat.821

データ提供:米国国立医学図書館(NLM)

Anticholinergics: Navigating the Desert of Side Effects

The world of [pharmaceuticals] is filled with [diverse medications], each with its own [unique properties] and [potential side effects]. This study explores the [effects of various anticholinergics] on [acoustic startle response] in [rats]. It's like traversing a desert landscape, carefully evaluating different plants for their potential benefits and risks. The researchers investigated the [impact of these drugs] on [various measures] of [startle response], allowing for a comprehensive analysis of their [pharmacological effects].

Anticholinergic Effects: A Desert Landscape of Side Effects

The study revealed that [different anticholinergics] had [variable effects] on [acoustic startle response]. It’s like encountering different types of desert vegetation, each with its own unique characteristics. Some drugs [increased startle amplitude], while others [decreased latency] or [affected prepulse inhibition]. These findings highlight the [importance of carefully selecting] [anticholinergic medications] to [minimize potential side effects] and [optimize treatment outcomes].

A Careful Journey: Selecting the Right Anticholinergics

This study emphasizes the [need for precision] in [prescribing anticholinergics]. It's like carefully choosing the right camel for a desert journey, where each camel has its own strengths and weaknesses. The research suggests that [acoustic startle response] can be a [valuable tool] for [identifying] [anticholinergics] with [minimal side effects] and [optimal efficacy]. This approach can help ensure that patients receive the [most appropriate treatment] with the [least risk of unwanted consequences].

Dr.Camel's Conclusion

This research highlights the importance of understanding the specific effects of different anticholinergics on acoustic startle response. It’s like carefully navigating a desert landscape, where each path has its own unique hazards. By understanding these nuances, clinicians can better select anticholinergic medications that offer optimal efficacy with minimal side effects, leading to better patient outcomes. It's a reminder that careful consideration is key to a safe and effective journey through the desert of pharmacological treatments.

Date :
  1. Date Completed 2002-04-18
  2. Date Revised 2019-09-22
Further Info :

Pubmed ID

11920928

DOI: Digital Object Identifier

10.1002/jat.821

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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