[Penetration and side effects of local estrogen application in alopecia androgenetica].

Author: OrfanosC E, WüstnerH

Paper Details 
Original Abstract of the Article :
In 30 male patients aged 17-37 with definite androgenetic ("male pattern") alopecia (AA, telogen hair rate greater than 20%) the total urinary estrogen level was estimated before and after topical treatment: In 18 patients estrogen in a alcoholic vehicle (0.05% dienestroldiacetate) was daily applied...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1213890

データ提供:米国国立医学図書館(NLM)

Investigating the Potential of Topical Estrogen for Androgenetic Alopecia

This research delves into the intriguing world of [androgenetic alopecia (AA)] treatment. The researchers are exploring the potential of a topical estrogen application as a therapeutic approach for this common hair loss condition. They conducted a study involving 30 male patients with AA, carefully dividing them into two groups: one receiving topical estrogen and the other a control group. They closely monitored the urinary estrogen levels and observed the clinical effects over a period of six months.

Estrogen Application: A Safe and Potentially Effective Approach?

The study revealed that topical estrogen application did not lead to any significant changes in urinary estrogen levels, nor were there any notable adverse effects, such as gynecomasty. This suggests that long-term topical estrogen treatment might be a safe option for adult males, potentially offering a new avenue for treating androgenetic alopecia.

Estrogen's Local Mechanism of Action

The researchers propose that the potential efficacy of estrogen in AA may stem from a local mechanism of action directly on the hair follicles. This hypothesis, while intriguing, requires further investigation to validate its accuracy.

Dr.Camel's Conclusion

The desert winds of scientific discovery have blown a new path for treating androgenetic alopecia. This research suggests that topical estrogen could be a safe and effective treatment option. However, like a desert oasis, this discovery needs further exploration to uncover its full potential.

Date :
  1. Date Completed 1976-04-10
  2. Date Revised 2006-11-15
Further Info :

Pubmed ID

1213890

DOI: Digital Object Identifier

1213890

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SNS
PICO Info
in preparation
Languages

German

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