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Oral administration of freshly expressed juice of Echinacea purpurea herbs fail to stimulate the nonspecific immune response in healthy young men: results of a double-blind, placebo-controlled crossover study.

Author: BodeChristiane, BodeJ Christian, DiedrichJens P, FreudensteinJohannes, MetzlerJoerg, SchwarzEveline

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the effects of orally consumed Echinacea purpurea on the immune system of 40 healthy men. Contrary to previous research that suggested Echinacea could boost the immune system in lab settings or when injected, this study found no evidence that oral Echinacea increased phagocytic activity or the production of immune-boosting proteins (TNF-alpha and IL-1beta). Interestingly, Echinacea did lower iron levels in the blood. While the study did not confirm the immune-boosting effects of Echinacea, it suggests that other mechanisms may explain its benefits in reducing the duration and severity of colds, as observed in previous clinical trials.
Paper Details　
Original Abstract of the Article :
Echinacea extracts are widely used in European countries and in the United States as "immune-stimulating" agents. Even though the evidence to stimulate certain components of the nonspecific immune system (phagocytosis, macrophages, and production of cytokines) stems from in vitro experiments or stud...See full text at original site
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引用元：
https://doi.org/10.1097/00002371-200209000-00005

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 2003-03-03
  2. Date Revised 2019-11-06
Further Info :

Pubmed ID

12218779

DOI: Digital Object Identifier

10.1097/00002371-200209000-00005

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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