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Adjuvant therapy of malignant melanoma.

Author: HancockB W, MolifeR

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

While adjuvant therapy is considered for high-risk melanoma, early trials of various agents like BCG, levamisole, and chemotherapy showed largely negative results. Interferon is the only therapy to show a significant benefit in randomized controlled trials for melanoma.
Paper Details　
Original Abstract of the Article :
High risk surgically resected melanoma is associated with a less than 50% 5-year survival. Adjuvant therapy is an appropriate treatment modality in this setting, and is more likely to be effective as the tumour burden here is small. Clinical observations of spontaneous tumour regressions and a highl...See full text at original site
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引用元：
https://doi.org/10.1016/s1040-8428(02)00014-8

データ提供：米国国立医学図書館（NLM）

Fighting Melanoma: Exploring Adjuvant Therapies

This research reviews the current state of adjuvant therapy for malignant melanoma, a type of skin cancer with a high risk of recurrence. The study examines the effectiveness of various adjuvant therapies, including vaccines and interferons, in improving survival rates for patients with high-risk melanoma. The authors conclude that interferon is the only therapy to have shown a significant benefit in randomized controlled trials. However, they also acknowledge the need for further research to confirm the role of adjuvant therapies in managing high-risk melanoma and improving long-term outcomes for patients.

A Desert of Possibilities: Adjuvant Therapies for Melanoma

This research delves into the complex and evolving landscape of adjuvant therapies for melanoma. The authors meticulously reviewed the existing literature, evaluating the effectiveness of various treatments in improving survival rates for patients with high-risk melanoma. It’s like exploring a vast desert, where different paths lead to varying outcomes, and researchers are constantly seeking new and effective approaches to combat this challenging disease. This research provides a valuable overview of the current state of knowledge regarding adjuvant therapies for melanoma and highlights the need for continued research and development.

A Hopeful Oasis: Adjuvant Therapies and Melanoma Treatment

This study underscores the importance of ongoing research in developing effective adjuvant therapies for melanoma. The authors highlight the limitations of current treatment options and the need for innovative approaches to improve long-term outcomes for patients. As a concerned medical professional, I encourage individuals diagnosed with melanoma to consult with a qualified oncologist to discuss the most appropriate treatment plan. It’s like finding a source of water in a barren desert, offering hope and support in the fight against this challenging disease.

Dr.Camel's Conclusion

This systematic review provides a comprehensive overview of the current state of adjuvant therapy for malignant melanoma. The findings highlight the need for continued research to identify effective treatment strategies and improve long-term outcomes for patients with high-risk melanoma.
Date :
  1. Date Completed 2003-07-02
  2. Date Revised 2019-11-06
Further Info :

Pubmed ID

12399001

DOI: Digital Object Identifier

10.1016/s1040-8428(02)00014-8

Related Literature

Article Analysis
・Effective treatment of melanoma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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