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Vaginal micronized progesterone in continuous hormone replacement therapy. A prospective randomized study.

Author: CristoforoniP, FerreroS, FulcheriE, GerbaldoD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Progestins, when co-administered with estrogen replacement therapy in post-menopausal women, are essential to counter the proliferative effect of estrogen on the endometrium. This study investigated the effects of different progestins on lipid profiles and endometrial morphology, revealing varying metabolic and tissue effects depending on dosage and administration route.
Paper Details　
Original Abstract of the Article :
In the non-hysterectomized post-menopausal woman undergoing estrogen replacement therapy, the co-administration of a progestogen is mandatory to counteract the estrogenic proliferative effect on the endometrium. Metabolic and tissue effects of the various progestins vary with dosage and route of adm...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12432337

データ提供：米国国立医学図書館（NLM）

Vaginal Micronized Progesterone: A Balancing Act in Hormone Replacement Therapy

Hormone replacement therapy (HRT) is a complex field, much like a desert with a delicate ecosystem. This study examines the effects of vaginal micronized progesterone, a common component of HRT, on lipid profiles and endometrial morphology. The authors conducted a randomized controlled trial to evaluate the effects of different progestins on the lipid profile and endometrial morphology of post-menopausal women undergoing estrogen replacement therapy.

Navigating the Desert of Menopause

This study highlights the importance of finding the right balance when navigating the desert of menopause. It emphasizes the need to consider the individual risks and benefits of different progestins, as well as the impact of dosage and route of administration.

Making Informed Decisions in the Desert of HRT

For women considering HRT, this research serves as a valuable reminder to consult with a healthcare professional for personalized advice. It emphasizes the importance of understanding the potential effects of various progestins and choosing the best option based on individual needs and health status.

Dr.Camel's Conclusion

This research underscores the intricate complexities of hormone replacement therapy. It highlights the importance of carefully considering the specific needs of each individual and choosing the most appropriate progestin for a balanced and effective treatment approach.

Date :
  1. Date Completed 2003-09-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

12432337

DOI: Digital Object Identifier

12432337

Related Literature

Article Analysis
・Effects of progesterone
SNS
PICO Info
in preparation
Languages

English

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