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Epoetin alfa treatment results in clinically significant improvements in quality of life in anemic cancer patients when referenced to the general population.

Author: CellaDavid, GagnonDennis D, HurtzHans-Jürgen, NortierJohan W R, VandorosChristina, ZagariMartin J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.

Overview

While epoetin alfa has been shown to increase hemoglobin levels, reduce fatigue, and improve overall quality of life (QOL) in cancer patients with anemia, the condition remains undertreated. This study highlights the need for better understanding and implementation of QOL measures in clinical practice.
Paper Details　
Original Abstract of the Article :
Anemia, highly common among cancer patients, is often an underlying cause of cancer-related fatigue and other quality-of-life (QOL) deficits. Although randomized clinical trials have shown that treatment with epoetin alfa increases hemoglobin levels, reduces fatigue, lessens transfusion requirements...See full text at original site
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引用元：
https://doi.org/10.1200/JCO.2003.02.136

データ提供：米国国立医学図書館（NLM）

Improving Quality of Life for Anemic Cancer Patients

This study explores the impact of epoetin alfa, a drug that stimulates red blood cell production, on the quality of life (QOL) of anemic cancer patients. The researchers highlighted the significant role of anemia in contributing to cancer-related fatigue and other QOL deficits. They analyzed data from clinical trials that demonstrated epoetin alfa's efficacy in increasing hemoglobin levels, reducing fatigue, and improving overall QOL. The study addressed the challenges in interpreting clinical trial results due to the lack of standardized QOL measures and population-based reference ranges.

Epoetin Alfa: A Game Changer for Anemic Cancer Patients

This study emphasizes the profound impact of epoetin alfa on the quality of life of anemic cancer patients. The researchers found that epoetin alfa effectively improved hemoglobin levels, alleviated fatigue, and reduced the need for blood transfusions, leading to significant improvements in overall QOL. These findings underscore the importance of addressing anemia in cancer patients, as it can significantly impact their well-being.

The Importance of Personalized Care in Cancer Management

This study highlights the need for personalized care in cancer management, considering the specific needs of each patient. Assessing QOL and addressing anemia are crucial aspects of providing comprehensive care to cancer patients. By understanding the impact of anemia on a patient's well-being, healthcare professionals can develop tailored treatment plans to improve their quality of life.

Dr.Camel's Conclusion

This study, like a camel seeking an oasis in a parched desert, sheds light on the importance of addressing anemia in cancer patients. It underscores the effectiveness of epoetin alfa in improving their quality of life, demonstrating the transformative power of effective treatment. This research serves as a reminder to prioritize the well-being of cancer patients and ensure they receive the best possible care throughout their journey.

Date :
  1. Date Completed 2003-02-04
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

12525531

DOI: Digital Object Identifier

10.1200/JCO.2003.02.136

Related Literature

Article Analysis
・Effective treatment of anemia
SNS
PICO Info
in preparation
Languages

English

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