High-dose, short-duration, early valacyclovir therapy for episodic treatment of cold sores: results of two randomized, placebo-controlled, multicenter studies.

Author: BarberJudy, BlatterMark M, GoldsteinDonna, HillJoanne, JonesTerry M, SchultzMargaret, SpruanceSpotswood L, Vargas-CortesMauricio

Paper Details 
Original Abstract of the Article :
Oral valacyclovir is better absorbed than oral acyclovir, increasing acyclovir bioavailability three- to fivefold. This provides the opportunity to explore whether high systemic acyclovir concentrations are effective in the treatment of cold sores (herpes labialis). Two randomized, double-blind, pla...See full text at original site
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引用元:
https://doi.org/10.1128/AAC.47.3.1072-1080.2003

データ提供:米国国立医学図書館(NLM)

A Speedy Cure for Cold Sores

Cold sores, those pesky little blisters, can be a real nuisance. This research focuses on a faster way to treat cold sores using valacyclovir, a drug that's better absorbed than its cousin, acyclovir. They investigated the effectiveness of high-dose, short-duration valacyclovir therapy in two clinical trials. The results demonstrated that a one-day treatment regimen of valacyclovir can significantly reduce the duration of cold sores, making it a convenient and effective treatment option.

A One-Day Wonder

The research shows that a one-day treatment with valacyclovir can significantly shorten the duration of cold sores compared to placebo. The study found that the median duration of cold sores was reduced by one day with the one-day treatment, and the mean duration was reduced by 1.1 days. These findings suggest that a one-day treatment with valacyclovir could be a valuable tool for treating cold sores quickly and efficiently.

A Boon for Cold Sore Sufferers

For those who dread the appearance of cold sores, a one-day treatment could be a game-changer. Imagine a quick and easy way to alleviate the pain and discomfort associated with cold sores. The findings suggest that this treatment option could offer a significant improvement in the lives of people who frequently suffer from cold sores.

Dr.Camel's Conclusion

Cold sores can be a real drag, like a pesky camel fly buzzing around your head in the desert. This research provides a refreshing solution with a one-day treatment option that could quickly put a stop to those pesky blisters. It's a convenient and effective approach that could leave those suffering from cold sores feeling much better, like a camel finding a patch of lush greenery in the middle of the sand dunes.

Date :
  1. Date Completed 2003-08-14
  2. Date Revised 2021-05-26
Further Info :

Pubmed ID

12604544

DOI: Digital Object Identifier

10.1128/AAC.47.3.1072-1080.2003

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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