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Dermatologic side effects of thalidomide in patients with multiple myeloma.

Author: BouwhuisSaskia, El-AzharyRokea A, HallVirginia C, RajkumarS Vincent

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Thalidomide treatment can cause dermatologic side effects, with a higher prevalence than previously reported. These side effects are usually minor but can be severe, particularly when thalidomide is given with dexamethasone.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Thalidomide, an antiangiogenic agent, was approved by the Food and Drug Administration in 1998 for the treatment of erythema nodosum leprosum. Although its teratogenic and neurologic side effects are well known, its dermatologic side effects continue to be defined. OBJECTIVE: We report ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12664018

データ提供：米国国立医学図書館（NLM）

Thalidomide: Navigating the Shifting Sands of Side Effects

Thalidomide, a drug known for its devastating teratogenic effects, has recently emerged as a potential treatment for multiple myeloma. This study explores the dermatologic side effects of thalidomide in patients with multiple myeloma, seeking to understand the potential risks and benefits associated with this promising but complex medication. It's like navigating a shifting desert landscape, where the path forward can be unpredictable and fraught with potential dangers.

Unveiling the Dermatologic Landscape

The study found that dermatologic side effects, ranging from mild to severe, were common in patients receiving thalidomide. These findings highlight the importance of careful monitoring for skin reactions and prompt intervention when necessary, ensuring a safer and more comfortable experience for patients undergoing treatment with thalidomide.

Balancing the Risks and Benefits

This study provides valuable information for healthcare professionals in managing the use of thalidomide for multiple myeloma. It underscores the importance of carefully weighing the potential benefits of thalidomide against the risks of dermatologic side effects. Just like a camel navigating a treacherous desert, we need to be aware of the potential hazards and take appropriate precautions to ensure a safe journey.

Dr.Camel's Conclusion

This study reinforces the importance of a nuanced approach to drug therapy, carefully considering both the potential benefits and the risks of any medication. By understanding the dermatologic side effects associated with thalidomide, we can provide patients with informed consent and appropriate monitoring, ensuring a safer and more comfortable experience as they navigate the challenging terrain of multiple myeloma treatment.

Date :
  1. Date Completed 2003-04-22
  2. Date Revised 2018-04-14
Further Info :

Pubmed ID

12664018

DOI: Digital Object Identifier

S0190-9622(02)61491-4

Related Literature

Article Analysis
・Side Effects of thalidomide
SNS
PICO Info
in preparation
Languages

English

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