Paper Details

  1. Home
  2. Paper Details

Treatment perspectives for human African trypanosomiasis.

Author: BisserSylvie, BouteilleBernard, DumasMichel, OukemOdile

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Human African trypanosomiasis, or sleeping sickness, is a fatal disease with limited therapeutic options. Research and development for new drugs is limited, but efforts are focused on reevaluating older drugs and investigating drug combinations.
Paper Details　
Original Abstract of the Article :
Human African trypanosomiasis (HAT), or sleeping sickness, is currently on the rise. HAT develops in two stages, the first involving the hemolymphatic system, and the second, the neurological system. Left untreated, HAT is invariably fatal. There have been no therapeutic advances in more than 40 yea...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1046/j.1472-8206.2003.00167.x

データ提供：米国国立医学図書館（NLM）

Human African Trypanosomiasis: A Race Against Time

This research explores the current treatment options for Human African Trypanosomiasis (HAT), also known as sleeping sickness. The study highlights the urgent need for new therapeutic approaches, as current treatments are often toxic and limited in their effectiveness. The research examines the effectiveness of existing drugs, such as pentamidine, suramin, melarsoprol, and eflornithine, and discusses the potential of new drug candidates and combination therapies.

A Daunting Challenge: The Need for New Treatments for HAT

The study underscores the significant challenges in treating HAT, a debilitating and often fatal disease. The limited availability of effective and safe treatments, coupled with the emergence of drug resistance, highlights the urgent need for new drug development. The research discusses the potential of a new pentamidine analog, currently in clinical development, and emphasizes the importance of reevaluating older drugs and exploring combination therapies to improve treatment outcomes.

The Quest for a Cure: A Collaborative Effort

This study underscores the importance of continued research and development in the fight against HAT. The research highlights the need for collaborative efforts between scientists, clinicians, and public health officials to develop new treatments that are more effective, safer, and more widely accessible.

Dr.Camel's Conclusion

This research paints a stark picture of the challenges in treating HAT. The study highlights the urgent need for new and improved treatment options to combat this devastating disease. The call for collaborative efforts and continued research is a crucial step toward finding a cure for HAT and ensuring that all individuals have access to effective treatment.

Date :
  1. Date Completed 2003-08-29
  2. Date Revised 2019-10-25
Further Info :

Pubmed ID

12667227

DOI: Digital Object Identifier

10.1046/j.1472-8206.2003.00167.x

Related Literature

Article Analysis
・Side Effects of pentamidine injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.