A prospective randomized trial of diltiazem and glyceryltrinitrate ointment in the treatment of chronic anal fissure.

Author: BieleckiK, KolodziejczakM

Paper Details 
Original Abstract of the Article :
OBJECTIVE: The aim of this study was to compare prospectively diltiazem with GTN ointment in the treatment of anal fissure. PATIENTS AND METHODS: Of 43 outpatients with chronic anal fissure, 22 patients were randomized to topical diltiazem (2%) ointment and 21 patients to glyceryltrinitrate (GTN) (...See full text at original site
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引用元:
https://doi.org/10.1046/j.1463-1318.2003.00440.x

データ提供:米国国立医学図書館(NLM)

Diltiazem vs. Glyceryltrinitrate Ointment for Chronic Anal Fissure

This study delves into a common and often bothersome condition, chronic anal fissure. The research compares the effectiveness of two topical treatments: diltiazem and glyceryltrinitrate (GTN) ointment. Through a prospective randomized trial, researchers investigated the healing rates and side effects associated with each treatment. They found that both treatments were equally effective, but diltiazem was associated with fewer side effects.

Finding Relief: A Comparison of Treatments

The study reveals that diltiazem and GTN ointment are equally effective in healing chronic anal fissures, but diltiazem might be a better choice due to its lower side effect profile. This finding provides valuable information for clinicians seeking to provide effective and well-tolerated treatment for this common condition. It's like having two routes through a desert, one smooth and straightforward, the other challenging and bumpy, ultimately leading to the same destination.

Easing the Discomfort: Choosing the Right Treatment

This research offers insights into the potential benefits of diltiazem for chronic anal fissures. The study suggests that diltiazem might be a preferred treatment due to its lower side effect profile, providing a more comfortable and tolerable experience for patients. It's like finding a cool oasis in a hot desert, offering relief and comfort in the face of a challenging condition.

Dr.Camel's Conclusion

This study provides valuable insights into the treatment of chronic anal fissures, comparing the effectiveness of diltiazem and GTN ointment. The findings highlight the potential of diltiazem as a preferred treatment option due to its lower side effect profile, offering a more comfortable and well-tolerated approach to managing this common condition.

Date :
  1. Date Completed 2003-07-16
  2. Date Revised 2019-11-07
Further Info :

Pubmed ID

12780888

DOI: Digital Object Identifier

10.1046/j.1463-1318.2003.00440.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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