Anesthetics inhibit high-affinity states of dopamine D2 and other G-linked receptors.

Author: KapurShitij, SeemanPhilip

Paper Details 
Original Abstract of the Article :
The high-affinity states of dopamine D2 and D3 receptors, serotonin 5HT-2A receptors, beta-2-adrenoceptors, alpha-1 and alpha-2 adrenoceptors, opiate receptors, and muscarinic receptors were inhibited by clinical concentrations of anesthetics, including isoflurane, halothane, chloral hydrate, ketami...See full text at original site
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引用元:
https://doi.org/10.1002/syn.10221

データ提供:米国国立医学図書館(NLM)

Anesthetics: A Deeper Dive into the Molecular Mechanisms of Sleep

The world of anesthesia is like a vast and mysterious desert, where the mechanisms of sleep and unconsciousness remain shrouded in mystery. This study takes a closer look at the molecular mechanisms behind general anesthesia, exploring the effects of various anesthetics on G-protein-linked receptors, which are like the gatekeepers of cellular communication. The authors found that anesthetics can inhibit the high-affinity states of these receptors, which may explain how anesthetics induce unconsciousness. This research offers a deeper understanding of the molecular mechanisms that govern general anesthesia, paving the way for a more precise and targeted approach to the management of pain and consciousness.

Unraveling the Mysteries of General Anesthesia

The study sheds light on the complex interplay between anesthetics and G-protein-linked receptors, revealing the intricate molecular mechanisms that underpin general anesthesia. This research suggests that the inhibition of these receptors by anesthetics may be a key factor in inducing unconsciousness. This knowledge is crucial for understanding how anesthetics work and for developing new and safer anesthetic agents, much like a desert explorer meticulously studying the terrain to find the best route to their destination.

Navigating the Desert of Consciousness: A More Precise Approach to Anesthesia

This research opens up new avenues for understanding and managing general anesthesia, much like a desert explorer discovering new trails leading to a more favorable oasis. With a deeper understanding of the molecular mechanisms involved, we can strive for more precise and targeted anesthetic agents, minimizing side effects and ensuring patient safety. This research is a testament to the power of scientific inquiry in unraveling the mysteries of the desert of consciousness.

Dr.Camel's Conclusion

This study delves into the fascinating molecular mechanisms of general anesthesia, offering a deeper understanding of the desert of consciousness. The authors provide valuable insights into how anesthetics interact with G-protein-linked receptors, revealing the intricate pathways leading to unconsciousness. This research paves the way for a more precise and targeted approach to anesthesia, offering a more comfortable and safe journey for patients.

Date :
  1. Date Completed 2003-12-12
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

12872292

DOI: Digital Object Identifier

10.1002/syn.10221

Related Literature

SNS
PICO Info
in preparation
Languages

English

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