Anti-addictive actions of an iboga alkaloid congener: a novel mechanism for a novel treatment.

Author: GlickStanley D, MaisonneuveIsabelle M

Paper Details 
Original Abstract of the Article :
18-Methoxycoronaridine (18-MC), a novel iboga alkaloid congener that decreases drug self-administration in several animal models, may be a potential treatment for multiple forms of drug abuse. In animal models, 18-MC reduced intravenous morphine, cocaine, methamphetamine and nicotine self-administra...See full text at original site
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引用元:
https://doi.org/10.1016/s0091-3057(03)00119-9

データ提供:米国国立医学図書館(NLM)

A Novel Approach to Combatting Addiction

Drug addiction is a complex and challenging problem, affecting millions worldwide. This research explores the potential of a novel iboga alkaloid congener, 18-methoxycoronaridine (18-MC), as a potential treatment for various forms of drug abuse. The study investigated the effects of 18-MC on drug self-administration in animal models, demonstrating its effectiveness in reducing drug-seeking behavior across multiple substances. The researchers identified a potential mechanism of action for 18-MC, focusing on its antagonist activity at alpha3beta4 nicotinic receptors.

Unlocking New Pathways for Addiction Treatment

This research offers a glimmer of hope for individuals struggling with addiction. The study suggests that 18-MC, by targeting alpha3beta4 nicotinic receptors, might offer a novel approach to treating a wide range of addictive disorders. This promising new avenue for research could lead to the development of effective treatments that address the multifaceted nature of addiction.

A New Frontier in Addiction Research

This study opens a new frontier in addiction research, offering a potentially transformative approach to treating addiction. Like a camel discovering a new oasis in the desert, this research offers a refreshing perspective on combating drug abuse, potentially leading to more effective treatment options for individuals seeking recovery.

Dr. Camel's Conclusion

This research provides a promising new avenue for combatting the scourge of addiction. The potential of 18-MC to address a wide range of addictive behaviors offers a beacon of hope for individuals seeking recovery. Like a camel navigating the vast and challenging desert landscape, this research offers a potential path towards a brighter future, free from the grip of addiction.

Date :
  1. Date Completed 2004-04-08
  2. Date Revised 2019-07-12
Further Info :

Pubmed ID

12895678

DOI: Digital Object Identifier

10.1016/s0091-3057(03)00119-9

Related Literature

SNS
PICO Info
in preparation
Languages

English

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