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Lipid-lowering drugs and serum liver enzymes: the effects of body weight and baseline enzyme levels.
Author: ElisafMoses S, HatzidimouKaterina, KiortsisDimitrios N, NikasSpyridon, TsianosEpaminondas
Original Abstract of the Article :
The most important side effects of fibrate and 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor (statin) treatment are hepatic toxicity and myopathy. Obese individuals may have higher levels of serum transaminases than their lean counterparts. The main purpose of this study was to...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1046/j.1472-8206.2003.00176.x
データ提供:米国国立医学図書館(NLM)
Lipid-Lowering Drugs and Liver Enzymes: Exploring the Effects of Body Weight
In the vast and ever-changing landscape of cardiovascular health, managing cholesterol levels is crucial. This research explores the effects of lipid-lowering drugs, like fibrates and statins, on liver enzymes. These drugs are like desert oases, helping to quench the thirst of high cholesterol, but they may also have unexpected effects on the liver. The authors delve into the potential impact of body weight on these effects, much like the influence of rainfall on desert vegetation.
The Impact of Body Weight on Liver Enzymes
This research emphasizes the importance of considering body weight when prescribing lipid-lowering medications. The authors found that obese patients tend to have higher levels of liver enzymes compared to their leaner counterparts. However, they also found that both fibrates and statins are generally safe for obese patients and those with moderately elevated liver enzymes. This is a reassuring discovery, like finding a hidden spring in the desert, offering hope for managing cholesterol safely in diverse populations.
Staying Healthy While Managing Cholesterol
As you navigate the desert of cholesterol management, remember that maintaining a healthy weight is crucial. It's also essential to communicate openly with your doctor about any potential side effects you experience while taking lipid-lowering medications. Like a wise camel, listen to your body and seek professional guidance when needed. By working together, you can find a safe and effective approach to managing your cholesterol and maintaining overall health.
Dr.Camel's Conclusion
This research highlights the importance of understanding the interplay between body weight, lipid-lowering drugs, and liver enzymes. It provides valuable information for healthcare professionals and individuals seeking to manage cholesterol safely and effectively. Remember, like the desert, our bodies are complex and require careful attention to maintain balance and health.
Date :
- Date Completed 2004-01-23
- Date Revised 2022-03-30
Further Info :
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