Effects of mebendazole, albendazole, and praziquantel on alkaline phosphatase, acid phosphatase, and adenosine triphosphatase of Echinococcus granulosus cysts harbored in mice.

Author: ChaiJ J, FengJ J, GuoH F, JiaoP Y, RenL, XiaoS H, YaoM Y

Paper Details 
Original Abstract of the Article :
Mice infected with protoscoleces of Echinococcus granulosus for 12-14 months were treated ig with mebendazole (Meb) 25-50 mg.kg-1 x d-1 for 7-14 d, albendazole (Alb) 200 mg.kg-1 x d-1, cr praziquantel (Pra) 500 mg.kg-1 x d-1 for 14 d. The mice were killed 24 h after the last medication, and acid pho...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1302436

データ提供:米国国立医学図書館(NLM)

Echinococcus granulosus: A Challenge in the Desert of Parasitology

The world of parasitology is vast and complex, with a myriad of organisms seeking to thrive at the expense of their hosts. Echinococcus granulosus is one such parasite, responsible for causing hydatid disease, a serious condition that can have devastating consequences. This research explores the effects of various antiparasitic drugs on the parasite's enzymes, aiming to develop more effective treatments.

The authors investigated the effects of mebendazole, albendazole, and praziquantel on the enzymatic activity of Echinococcus granulosus cysts. They found that these drugs had varying effects on different enzymes, suggesting that the mechanisms of action of these drugs are not identical. This research provides valuable insights into the potential of these drugs in combating hydatid disease, offering hope for a more effective approach to treating this challenging parasitic infection.

Unveiling the Secrets of Parasite Enzymes

This research offers a glimpse into the intricate world of parasitic enzymes, revealing the potential of specific drugs to target and inhibit their activity. The findings provide valuable insights for developing more effective therapies for hydatid disease and other parasitic infections. It's a reminder that understanding the mechanisms of action of these drugs is crucial in designing successful treatments.

Fighting Parasitic Infections: A Continuous Struggle

The research on Echinococcus granulosus and the effects of various drugs on its enzymes provides valuable information for developing more effective therapies for hydatid disease. It highlights the ongoing battle against parasitic infections and the importance of research in finding new solutions.

Dr. Camel's Conclusion

This research delves into the intricate world of parasitic enzymes, revealing the potential of specific drugs to target and inhibit their activity. It offers insights into the mechanisms of action of these drugs and their potential in combating hydatid disease, emphasizing the importance of ongoing research in finding effective treatments for parasitic infections.

Date :
  1. Date Completed 1993-06-09
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1302436

DOI: Digital Object Identifier

1302436

Related Literature

SNS
PICO Info
in preparation
Languages

English

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