Comparative clinical profiles of triazolam versus other shorter-acting hypnotics.

Author: ColemanB S, JonasJ M, KalinskeR W, SheridanA Q

Paper Details 
Original Abstract of the Article :
The efficacy, safety, and performance of triazolam was compared with those of other shorter-acting hypnotics acting on the gamma-aminobutyric acid (GABA) receptor--zopiclone, zolpidem, midazolam, brotizolam, temazepam, lormetazepam, and loprazolam. In all, 5506 patients participated in 38 clinical a...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/1336776

データ提供:米国国立医学図書館(NLM)

Triazolam and Other Hypnotics: Comparing Efficacy and Safety

In the field of sleep medicine, the search for effective and safe hypnotics is an ongoing journey. This study compared the efficacy, safety, and performance of triazolam to other short-acting hypnotics, including zopiclone, zolpidem, midazolam, brotizolam, temazepam, lormetazepam, and loprazolam. The researchers analyzed data from 38 clinical and epidemiological studies involving 5506 patients, with 2462 receiving triazolam. The study found no evidence of 'serious' central nervous system side effects, such as excitement or violence, with any of the hypnotic agents, including triazolam. Additionally, the study found remarkable similarities in terms of efficacy, side effects, and performance-related effects across all the shorter-acting agents, with zopiclone and zolpidem showing particular resemblance to triazolam.

Unveiling the Similarities in Hypnotic Medications

The study's findings highlight the similarities in the clinical and pharmacological profiles of various short-acting hypnotics, regardless of their chemical structure. These findings challenge previous assumptions about distinct effects associated with different drug classes and emphasize the importance of considering individual patient factors when selecting a suitable hypnotic medication.

Navigating the World of Sleep Aids: A Practical Approach

This study provides valuable information for patients and healthcare professionals seeking effective and safe sleep medications. It suggests that while individual preferences and sensitivities may vary, there is a remarkable consistency in the overall effects of short-acting hypnotics. It's essential to consult with a healthcare professional to determine the most appropriate sleep aid for individual needs and to discuss potential risks and benefits.

Dr. Camel's Conclusion

My dear friends, navigating the world of sleep aids can feel like traversing a vast desert with many paths. This study helps us understand that while the paths may seem different, they often lead to similar destinations. Remember to consult your doctor before embarking on any sleep-related journey, and choose the path that best suits your needs. Rest assured, there is a place for everyone to find restful slumber in the desert of sleep.
Date :
  1. Date Completed 1993-02-23
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

1336776

DOI: Digital Object Identifier

1336776

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.