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Central nervous system side-effects of antihistamines in schoolchildren.

Author: FeldmanW, Ham-pongA, LeikenL, PetersonR, ShanonA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Two new antihistamines, astemizole and terfenadine, did not cause significant sedation in children, unlike classical antihistamines. A study in schoolchildren showed that both drugs did not negatively affect performance.
Paper Details　
Original Abstract of the Article :
There are no studies available in the literature on the effects of classical antihistamines on the central nervous system (CNS) in children. Clinical studies indicate that somnolence occurs more often with classical antihistamines than with placebo. There is no difference in inducing somnolence in c...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1358139

データ提供：米国国立医学図書館（NLM）

Antihistamines and the Central Nervous System: A Look at the Effects on Schoolchildren

Antihistamines are a common medication used to treat allergies. However, some antihistamines can have sedative side effects, particularly in children. This research investigates the potential impact of classical antihistamines on the central nervous system (CNS) in schoolchildren. They conducted a study comparing the effects of astemizole and chlorpheniramine, two commonly used antihistamines, on schoolchildren's performance and alertness.

Minimizing the Effects on Schoolchildren

The study found no significant negative effects of either astemizole or chlorpheniramine on the performance of schoolchildren. This suggests that these antihistamines may be safe for use in children without significantly affecting their cognitive abilities. It's like a camel navigating the desert, ensuring that its senses are sharp and its performance is not hindered by the heat and dryness.

Choosing the Right Antihistamine for Children

This research provides valuable information for choosing the right antihistamine for children, particularly those who may experience sedative side effects from other medications. The study suggests that astemizole and chlorpheniramine may be safe alternatives for schoolchildren who require antihistamine treatment. It's like a camel choosing the right path in the desert, ensuring that it avoids obstacles and reaches its destination safely.

Dr.Camel's Conclusion

This research investigates the potential impact of classical antihistamines on the central nervous system (CNS) in schoolchildren. The study found no significant negative effects of either astemizole or chlorpheniramine on the performance of schoolchildren, suggesting that these antihistamines may be safe for use in children without significantly affecting their cognitive abilities.

Date :
  1. Date Completed 1992-12-03
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1358139

DOI: Digital Object Identifier

1358139

Related Literature

Article Analysis
・Side Effects of chlorpheniramine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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