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The relationship among previous antimicrobial use, antimicrobial resistance, and treatment outcomes for Helicobacter pylori infections.
Author: BenslerJ Michael, BruceMichael G, BrudenDana L, ButlerJay C, HennessyThomas W, HurlburtDebby A, McMahonBrian J, MorrisJulie M, ParkinsonAlan J, ReasonoverAlisa L, SaccoFrank
Original Abstract of the Article :
BACKGROUND: The relationship between previous antimicrobial treatments and infection with drug-resistant Helicobacter pylori is unknown. OBJECTIVES: To determine whether previous use of antimicrobial agents predicts subsequent antibiotic resistance of H. pylori and whether resistance affects treatm...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.7326/0003-4819-139-6-200309160-00008
データ提供:米国国立医学図書館(NLM)
Helicobacter pylori: A Persistent and Elusive Foe
Helicobacter pylori, a bacterium that infects the stomach, is a major cause of gastritis and ulcers. This study investigates the relationship between previous antimicrobial use and the development of antimicrobial resistance in H. pylori infections. The researchers found that prior use of macrolides and metronidazole, common antibiotics for treating H. pylori infections, significantly increased the risk of resistance to these drugs, highlighting the challenges in managing this infection.
The Cycle of Resistance
The study's findings, like a desert cycle of drought and rain, demonstrate the complex interplay between antibiotic use and resistance. The overuse and misuse of antibiotics can lead to the emergence of resistant strains, posing a significant challenge to effective treatment.
The Importance of Prudent Antibiotic Use
This research underscores the critical importance of responsible antibiotic use. It highlights the need for healthcare providers to prescribe antibiotics only when necessary and to avoid unnecessary overuse. This approach can help prevent the emergence of resistant strains and ensure the effectiveness of antibiotics in treating bacterial infections.
Dr. Camel's Conclusion
This research, like a compass guiding us through the vast desert of antimicrobial resistance, highlights the crucial role of prudent antibiotic use in managing H. pylori infections. By understanding the complex interplay between antibiotic use and resistance, healthcare providers can develop more effective strategies for controlling this persistent and elusive foe.
Date :
- Date Completed 2003-09-29
- Date Revised 2019-06-19
Further Info :
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English
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