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In-vitro activity of RP 59500, a semisynthetic streptogramin, against staphylococci and streptococci.

Author: PechèreJ C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the in vitro activity of RP 59500, a new injectable streptogramin antibiotic, against Gram-positive cocci. RP 59500 displayed similar activity to pristinamycin and was effective against a wide range of staphylococci and streptococci, including multi-resistant isolates.
Paper Details　
Original Abstract of the Article :
The in-vitro activity of RP 59500, an injectable streptogramin derived from pristinamycin, was determined by agar dilution and compared with that of pristinamycin. Two hundred and sixty-one recent clinical isolates of Gram-positive cocci were tested against both antibiotics. The two compounds displa...See full text at original site
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引用元：
https://doi.org/10.1093/jac/30.suppl_a.15

データ提供：米国国立医学図書館（NLM）

Assessing the Effectiveness of a New Streptogramin Antibiotic

Antibiotic resistance is a growing threat to public health, making it crucial to develop new drugs to combat resistant bacteria. This study investigates the in vitro activity of RP 59500, a semisynthetic streptogramin antibiotic, against a variety of staphylococcal and streptococcal strains.

The researchers compared the activity of RP 59500 to that of pristinamycin, another streptogramin antibiotic. They found that RP 59500 displayed similar activity against a wide range of staphylococcal and streptococcal strains, including those resistant to other antibiotics.

A Promising New Antibiotic

The study demonstrates the potential of RP 59500 as a promising new antibiotic for treating infections caused by resistant bacteria.

The Need for Further Research and Development

The study highlights the need for further research and development of RP 59500, including clinical trials to evaluate its effectiveness and safety in human patients.

Dr.Camel's Conclusion

The quest for new antibiotics to combat resistant bacteria is a challenging one, akin to navigating a treacherous desert. This study offers hope for a new weapon in our arsenal, demonstrating the potential of RP 59500 to effectively target resistant bacteria. Further research is crucial to bring this promising antibiotic to the forefront of clinical practice and help us overcome the growing threat of antibiotic resistance.

Date :
  1. Date Completed 1992-11-05
  2. Date Revised 2019-05-09
Further Info :

Pubmed ID

1399945

DOI: Digital Object Identifier

10.1093/jac/30.suppl_a.15

SNS
PICO Info
in preparation
Languages

English

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