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Thiamine, riboflavin, and pyridoxine deficiencies in a population of critically ill children.
Author: JacobsonB, LockitchG, MacNabA, QuigleyG, SeearM
Original Abstract of the Article :
The unexpected autopsy finding of Wernicke encephalopathy in three children who died after prolonged enteral feeding prompted us to examine the incidence of thiamine deficiency in three high-risk pediatric populations. We also measured riboflavin and pyridoxine activity in the same groups. We used a...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1016/s0022-3476(05)81140-0
データ提供:米国国立医学図書館(NLM)
Hidden in Plain Sight: Vitamin Deficiencies in Critically Ill Children
This research sheds light on the prevalence of vitamin deficiencies, particularly thiamine deficiency, in critically ill children. Imagine a thirsty traveler in the middle of a vast desert, desperately needing water. The study revealed that thiamine deficiency, a potentially fatal but treatable condition, was surprisingly common in children admitted to intensive care and those receiving intensive chemotherapy. The researchers used activated enzyme assays to assess the levels of thiamine, riboflavin, and pyridoxine in three groups of children: those receiving long-term nasogastric feeding, those admitted to pediatric intensive care, and those undergoing intensive chemotherapy.Hidden Dangers in the Sand
The study found that 12.5% of the children in intensive care and 66.7% of the children receiving chemotherapy had thiamine deficiency. It's like finding a hidden oasis in the desert, but instead of water, it's a critical need for a vital nutrient. Thiamine deficiency is a serious problem that can lead to Wernicke encephalopathy, a neurological disorder that can cause confusion, memory problems, and coma. The researchers concluded that thiamine deficiency is a common and potentially fatal problem in critically ill children, and it is likely underdiagnosed.Keeping a Watchful Eye on Our Little Ones
This study emphasizes the importance of routine vitamin assessments in critically ill children, especially those at high risk for malnutrition. It's like a watchful desert guide, keeping an eye out for signs of distress in the travelers. The study recommends that healthcare providers be vigilant in identifying and treating vitamin deficiencies in critically ill children, which can help to prevent serious complications and improve their overall health. It's a vital step in ensuring that our little ones are well-equipped to thrive, even in the most challenging of environments.Dr. Camel's Conclusion
The findings of this study serve as a wake-up call for healthcare providers to be more aware of the potential for thiamine deficiency in critically ill children. It emphasizes the importance of early detection and treatment of vitamin deficiencies to prevent serious health complications. It's a reminder that even in the most dire of circumstances, we can overcome challenges by being proactive and taking preventative measures.Date :
- Date Completed 1992-11-13
- Date Revised 2019-06-30
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