Paper Details

  1. Home
  2. Paper Details

Hematologic effects of linezolid in young children.

Author: BrussJon B, Edge-PadburyBarbara, KaplanSheldon L, MeissnerH Cody, MorfinMaria Rayo, Naberhuis-StehouwerSharon, TownsendTimothy, WenmanWanda

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Linezolid is an effective antibiotic for Gram-positive infections but can cause reversible blood cell suppression, particularly thrombocytopenia (low platelet count) with long-term use.
Paper Details　
Original Abstract of the Article :
Linezolid is an effective and well-tolerated antibiotic for the treatment of Gram-positive infections, including hospital and community-acquired pneumonia and complicated and uncomplicated skin and skin structure infections. In adults linezolid treatment for >/=2 weeks has been associated with rever...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1097/01.inf.0000087021.20838.d9

データ提供：米国国立医学図書館（NLM）

Hematologic Effects of Linezolid in Young Children

Linezolid is an antibiotic commonly used to treat infections caused by Gram-positive bacteria. This study examines the hematologic effects of linezolid in young children. Researchers, like skilled pediatricians carefully monitoring their young patients, are seeking to understand the potential side effects of this widely used antibiotic.

Linezolid: A Powerful Tool, But With Potential Side Effects

This study, like a desert explorer charting a new territory, reveals that linezolid treatment in young children, while generally well-tolerated, can be associated with reversible hematologic suppression, primarily thrombocytopenia. This finding, like a warning sign in the desert, emphasizes the importance of careful monitoring of hematologic parameters in young children receiving linezolid treatment.

Health Implications and Applications

This study, like a desert oasis providing essential resources, offers valuable information for clinicians treating young children with linezolid. It underscores the need for careful monitoring of platelet counts and other hematologic parameters to ensure the safe and effective use of this antibiotic.

Dr. Camel's Conclusion

This study, like a camel caravan navigating a vast and unforgiving desert, highlights the importance of careful monitoring when using linezolid in young children. It underscores the need for vigilance to ensure the safe and effective use of this valuable antibiotic.

Date :
  1. Date Completed 2003-11-12
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

14520145

DOI: Digital Object Identifier

10.1097/01.inf.0000087021.20838.d9

Related Literature

Article Analysis
・Effects of linezolid
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.