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The interaction between St John's wort and an oral contraceptive.

Author: AdigunAdegboyega Q, GorskiJ Christopher, HallStephen D, HammanMitchell A, HilligossJanna K, HuangShiew-Mei, MillerMargaret, VasavadaNina, WangZaiqi

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

St John's wort, a popular herbal remedy, can induce cytochrome P450 3A enzymes, potentially reducing the efficacy of oral contraceptives. Further research is needed to evaluate the effect of St John's wort on the efficacy of specific oral contraceptive pills.
Paper Details　
Original Abstract of the Article :
The popular herbal remedy St John's wort is an inducer of cytochrome P450 (CYP) 3A enzymes and may reduce the efficacy of oral contraceptives. Therefore we evaluated the effect of St John's wort on the disposition and efficacy of Ortho-Novum 1/35 (Ortho-McNeil Pharmaceutical, Inc, Raritan, NJ), a po...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/14663455

データ提供：米国国立医学図書館（NLM）

St. John's Wort and Oral Contraceptives: A Tale of Two Herbs in the Desert of Medication Interactions

The use of herbal remedies is increasingly popular, but it's important to be aware of potential interactions with other medications. This research explores the interaction between St. John's wort, a common herbal remedy, and Ortho-Novum 1/35, a combination oral contraceptive pill. The authors are like explorers charting the complex terrain of medication interactions, seeking to avoid unexpected consequences.

St. John's Wort: A Potential Pitfall in the Desert of Medication Interactions

The study found that St. John's wort can reduce the effectiveness of Ortho-Novum 1/35. This is like discovering a hidden pitfall in the desert, a potential obstacle that can lead to unforeseen consequences. The authors emphasize the importance of consulting with healthcare professionals before using herbal remedies alongside other medications.

Navigating the Desert of Medication Interactions: Staying Safe and Informed

This research underscores the importance of being informed about potential medication interactions, especially when using herbal remedies. It's crucial to discuss any herbal supplements with your doctor to ensure safe and effective medication management. This is like carrying a reliable map when navigating a desert, ensuring you avoid dangerous pitfalls and stay on the right path.

Dr.Camel's Conclusion

This research is a reminder that the desert of medication interactions is vast and unpredictable. It's essential to be aware of potential pitfalls, like the interaction between St. John's wort and oral contraceptives. By staying informed and consulting with healthcare professionals, we can safely navigate this complex terrain and maintain our health.

Date :
  1. Date Completed 2003-12-23
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

14663455

DOI: Digital Object Identifier

S0009923603002613

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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