[Effect of modified FLAG regimen therapy on 33 patients with relapsed/refractory leukemia].

Author: HuangFen, LiuQi-Fa, LiuXiao-Li, MengFan-Yi, SunJing, XuBing, YangLong-Jiang, ZhangYu, ZhengWei-Yang

Paper Details 
Original Abstract of the Article :
The hematological complete remission (CR) rate of the FLAG regimen [fludarabine and cytarabine (Ara-C) and granulocyte-colony stimulating factor] for relapsed and refractory acute non- lymphocytic leukemia (ANLL) was 50-64%. The aim of this study was to investigate the modified FLAG regimen (Ara-C r...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/14693062

データ提供:米国国立医学図書館(NLM)

Modified FLAG Regimen: A New Hope for Leukemia?

Leukemia research is a relentless pursuit, like a camel seeking a mirage in the desert. This study examines the effectiveness of a modified FLAG regimen, a potent cocktail of medications used to fight relapsed or refractory acute non-lymphocytic leukemia (ANLL). The original FLAG regimen, while effective, sometimes resulted in significant side effects. The researchers, driven by a thirst for improved treatment, sought to refine this regimen by reducing the dose of cytarabine and eliminating the use of granulocyte-colony stimulating factor (G-CSF) before the administration of fludarabine and Ara-C.

They meticulously analyzed the outcomes of this modified regimen in 33 patients. The results, like a shimmering oasis in the desert, showed promising signs of success. The modified FLAG regimen demonstrated comparable efficacy to the original regimen, but with potentially fewer side effects. This represents a significant advance in the quest for more tolerable leukemia treatments.

A Glimpse of Hope in the Treatment of Leukemia

The study's findings, like a beacon in the night, offer hope for individuals battling relapsed or refractory ANLL. The modified FLAG regimen holds the potential for better treatment outcomes, potentially improving the quality of life for patients. The authors emphasize the need for further investigation to confirm these early findings and to explore the long-term effects of this regimen.

A New Path for Leukemia Treatment

The pursuit of effective and safe treatment options for leukemia is an ongoing quest. This study, like a refreshing spring in the desert, provides a potential new pathway, offering hope for improved outcomes and reduced side effects. It is essential to continue researching and developing treatments for this devastating disease, always striving to create better outcomes for patients.

Dr.Camel's Conclusion

Leukemia is a challenging disease, but research, like a camel navigating the desert, relentlessly seeks solutions. This study offers a glimmer of hope with the potential of a modified FLAG regimen, a promising avenue for improved treatment outcomes with potentially fewer side effects. Further research is essential to fully explore the benefits of this modified approach, paving the way for a better future for those battling leukemia.

Date :
  1. Date Completed 2004-03-22
  2. Date Revised 2015-03-13
Further Info :

Pubmed ID

14693062

DOI: Digital Object Identifier

1000467X2003121330

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PICO Info
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Languages

Chinese

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