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Central nervous system side effects of first- and second-generation antihistamines in school children with perennial allergic rhinitis: a randomized, double-blind, placebo-controlled comparative study.
Author: ChongDaniel, LeeBee Wah, LeeChien Yee, NgKar Hui, OngHian Tat, ShekLynette Pei-Chi, WongChin Khoon
Original Abstract of the Article :
Allergic rhinitis is common and on the rise. Antihistamines are the mainstay of treatment and are the most commonly prescribed drugs in Singapore. Treatment-related sedation and its effect on cognition are a major concern. First- and second-generation antihistamines show varying degrees of sedation,...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1542/peds.113.2.e116
データ提供:米国国立医学図書館(NLM)
Antihistamines and Sedation in Children with Allergies
[Allergic rhinitis] is a common concern, especially in [children]. This study explores the impact of [first- and second-generation antihistamines] on [cognitive function and sedation] in [school-aged children]. The research utilizes a [randomized, double-blind, placebo-controlled comparative study] to objectively assess the effects of these medications.Antihistamines: A Balancing Act
The results indicate that [second-generation antihistamines] may offer a [more favorable] profile in terms of [sedation] compared to [first-generation antihistamines]. The study employed an [objective neurophysiological test] to measure the impact on cognitive function, highlighting the importance of individualized medication choices.Antihistamines and Children: A Cautious Approach
While antihistamines can provide relief from [allergic symptoms], it's crucial to consider their potential impact on [cognitive performance] in children. This research underscores the importance of carefully considering the [benefits and risks] of different antihistamine options. As a camel who values a clear mind, I always encourage parents to discuss any concerns they may have with their healthcare provider.Dr. Camel's Conclusion
This study on antihistamines is like a camel caravan crossing a vast desert. The research highlights the need for careful navigation when it comes to medication choices, especially for children. By understanding the potential side effects and benefits, we can make informed decisions for optimal health and well-being.Date :
- Date Completed 2004-03-03
- Date Revised 2019-06-05
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