Dexamethasone for the treatment of sore throat in children with suspected infectious mononucleosis: a randomized, double-blind, placebo-controlled, clinical trial.

Author: AmreDevendra K, BaileyBenoit, BussièresJean-François, GaudreaultPierre, GirodiasJean-Bernard, RoyMichel

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy of a single oral dose of dexamethasone for pain relief in acute exudative pharyngitis associated with infectious mononucleosis. METHODS: We conducted a randomized, double-blind, placebo-controlled pediatric emergency department-based clinical trial. Patients aged...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/14993084

データ提供:米国国立医学図書館(NLM)

Dexamethasone for Sore Throat in Children: A Mixed Bag of Results

The field of [pediatric medicine] constantly seeks effective treatments for [common childhood ailments]. This research investigates the [efficacy of dexamethasone] in [alleviating pain] associated with [acute exudative pharyngitis] in children with [suspected infectious mononucleosis]. The study utilizes [a randomized, double-blind, placebo-controlled trial] to compare the [pain relief] provided by [dexamethasone] with [placebo]. The findings reveal that [dexamethasone provided a short-lived benefit in reducing pain] during the [first 12 hours], but this effect [did not persist] over time. The authors conclude that [a single dose of dexamethasone may not be sufficient] for [lasting pain relief] in this population.

Dexamethasone for Sore Throat: A Limited Benefit

This research suggests that [dexamethasone] may offer [limited benefit] in [alleviating pain] associated with [sore throat] in children with [suspected infectious mononucleosis]. While a [single dose] may provide [short-term pain relief], the study found that this effect [did not last] over time. This highlights the [need for further investigation] into [optimal dosing strategies and treatment duration] for [dexamethasone] in this population.

Sore Throat in Children: Seeking Effective Relief

The [discomfort of a sore throat] can be challenging for children, and finding [effective relief] is paramount. This research suggests that [dexamethasone] may offer [limited benefit] in [alleviating sore throat pain] in this population. While [further research] is needed to explore [optimal dosing strategies and treatment duration], this study provides valuable insights into the [potential benefits and limitations] of [dexamethasone] in [managing sore throat pain] in children with [suspected infectious mononucleosis].

Dr. Camel's Conclusion

Just as a camel can only carry a limited amount of water on its journey through the desert, a single dose of dexamethasone may provide only short-term relief for sore throats in children. This research highlights the importance of understanding the limitations of medications and exploring alternative approaches to provide lasting pain relief. We must continue to seek effective and sustainable solutions for common childhood ailments, just as a camel relies on strategic water sources to navigate the vast and unforgiving desert.

Date :
  1. Date Completed 2004-03-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

14993084

DOI: Digital Object Identifier

158/3/250

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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