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Outcome of cabergoline treatment in men with prolactinoma: effects of a 24-month treatment on prolactin levels, tumor mass, recovery of pituitary function, and semen analysis.

Author: BrigantiFrancesco, CappabiancaPaolo, CiccarelliAntonio, ColaoAnnamaria, De RosaMichele, LombardiGaetano, VitaleGiovanni, ZarrilliStefano

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study prospectively investigated the outcome of 24 months of cabergoline treatment in men with macro- and microprolactinoma. Cabergoline treatment effectively normalized prolactin levels, reduced tumor size, restored pituitary function, and improved semen parameters.
Paper Details　
Original Abstract of the Article :
The outcome of 24 months of cabergoline treatment on prolactin (PRL) normalization, tumor shrinkage, restoration of pituitary function, and semen alterations was prospectively investigated in 41 men with macro- (age 17-70 yr) and 10 with microprolactinoma (age 18-53 yr). Fifty-one age-matched men se...See full text at original site
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引用元：
https://doi.org/10.1210/jc.2003-030979

データ提供：米国国立医学図書館（NLM）

Cabergoline: A Hopeful Solution for Men with Prolactinomas

Prolactinomas, benign tumors of the pituitary gland, can lead to a range of health problems, including infertility and hormonal imbalances. This study investigates the efficacy of cabergoline, a medication commonly used to treat prolactinomas, in men. The researchers sought to understand the long-term impact of cabergoline on prolactin levels, tumor size, pituitary function, and semen quality in men with prolactinomas.

A Journey to Hormone Harmony: Cabergoline for Men with Prolactinomas

This research, like a camel navigating a winding desert path, examines the effectiveness of cabergoline for men with prolactinomas. The study found that cabergoline treatment was effective in normalizing prolactin levels, reducing tumor size, and restoring pituitary function in most men. Furthermore, it demonstrated positive effects on semen quality, suggesting potential benefits for fertility in men with prolactinomas.

A Path to Fertility: Understanding Cabergoline's Role in Male Reproductive Health

This study sheds light on the potential of cabergoline to improve fertility in men with prolactinomas. The positive impact on semen quality offers a glimmer of hope for couples struggling with infertility due to prolactinomas. Like a camel navigating a vast desert to find a fertile oasis, this research provides valuable insights into the treatment of prolactinomas and its potential to restore reproductive health in men.

Dr. Camel's Conclusion

This study offers a promising outlook for men with prolactinomas, highlighting the effectiveness of cabergoline in treating this condition. It demonstrates the positive effects of cabergoline on prolactin levels, tumor size, pituitary function, and semen quality, suggesting a path towards improved health and reproductive well-being for men affected by prolactinomas.

Date :
  1. Date Completed 2004-05-11
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

15070934

DOI: Digital Object Identifier

10.1210/jc.2003-030979

Related Literature

Article Analysis
・Effects of cabergoline
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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