Improving phosphate-binder therapy as a way forward.

Author: HutchisonAlastair J

Paper Details 
Original Abstract of the Article :
Aluminium- or calcium-based phosphate-binding agents traditionally have been used to treat hyperphosphataemia in patients with end-stage renal disease. Although these agents effectively lower serum phosphorus levels, they are associated with serious side effects. Aluminium-based agents are associate...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15126650

データ提供:米国国立医学図書館(NLM)

Phosphate Binders: A Quest for a Safe Oasis in Kidney Disease

This study explores the challenges of managing hyperphosphataemia, a condition where phosphate levels in the blood are abnormally high, often seen in patients with end-stage renal disease. Traditional phosphate-binding agents, like those based on aluminum or calcium, have been effective in lowering phosphate levels, but they come with significant side effects. The authors discuss the need for new, safer alternatives, highlighting the development of sevelamer hydrochloride and lanthanum carbonate as promising options. Lanthanum carbonate, in particular, shows promising results in reducing phosphate levels while being well-tolerated and having a positive effect on bone health.

Finding a Path to Better Phosphate Management

The study highlights the progress made in finding safer and more effective treatments for hyperphosphataemia. Lanthanum carbonate, with its favorable safety profile and effectiveness in reducing phosphate levels, represents a significant step forward in managing this challenging condition.

Navigating the Sands of Kidney Disease

The research underscores the importance of ongoing research and development in the field of kidney disease, particularly in finding safe and effective treatments for hyperphosphataemia. The quest for better phosphate binders continues, with the goal of improving the lives of individuals with kidney disease.

Dr.Camel's Conclusion

This study illuminates the quest for safer and more effective treatments for hyperphosphataemia, offering hope for a more manageable path through the desert of kidney disease.

Date :
  1. Date Completed 2004-10-19
  2. Date Revised 2016-11-24
Further Info :

Pubmed ID

15126650

DOI: Digital Object Identifier

19/suppl_1/i19

Related Literature

SNS
PICO Info
in preparation
Languages

English

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